Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8664503 | 0.79 | SMN1; SMN2 (0.49) | MAPTSMN1; SMN2KDM4ETSHRHTT | |
| SCHEMBL8665479 | 0.73 | NPC1 (0.46) | MAPTSMN1; SMN2KDM4E | |
| SCHEMBL6994158 | 0.69 | LMNA (0.46) | MAPTSMN1; SMN2KDM4ETSHRHTT | |
| SCHEMBL18110503 | 0.65 | BRD4 (0.41) | MAPTSMN1; SMN2KDM4ETSHRHTT | |
| SCHEMBL18110505 | 0.65 | SMN1; SMN2 (0.39) | MAPTSMN1; SMN2KDM4EL3MBTL1TSHR | |
| SCHEMBL20298951 | 0.65 | AR (0.38) | MAPTSMN1; SMN2 | |
| SCHEMBL30100985 | 0.64 | BRD4 (0.40) | MAPTSMN1; SMN2KDM4ETSHRHTT | |
| SCHEMBL6989683 | 0.64 | TERT (0.40) | MAPTKDM4EL3MBTL1HTT | |
| SCHEMBL19690771 | 0.64 | — | — | |
| SCHEMBL8917481 | 0.64 | DRD3 (0.54) | KDM4ETSHRHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5574030-A | INHIBITING URINARY CONTRACTION, HETEROCYCLIC DIAMINES | NIPPON CHEMIPHAR CO., LTD. (JP) | 1996-11-12 | — | — | US | disclosed |