Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | LTA4H | P09960 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | PLK1 | P53350 | 2/20 | 0.48 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24200105 | 0.83 | CXCL8 (0.50) | L3MBTL1 | |
| SCHEMBL8086435 | 0.83 | CXCL8 (0.50) | L3MBTL1 | |
| SCHEMBL7332028 | 0.81 | MEN1 (0.45) | PLK1MEN1KMT2ASIGMAR1L3MBTL1 | |
| SCHEMBL3941649 | 0.78 | CXCL8 (0.54) | L3MBTL1TSHR | |
| SCHEMBL23229157 | 0.78 | CXCL8 (0.54) | POLBKMT2AL3MBTL1 | |
| SCHEMBL8998039 | 0.76 | CXCL8 (0.47) | L3MBTL1 | |
| SCHEMBL6689255 | 0.75 | ALDH1A1 (0.44) | POLBNPSR1PLK1MEN1KMT2A | |
| SCHEMBL8475269 | 0.74 | L3MBTL1 (0.74) | POLBMEN1KMT2AL3MBTL1 | |
| SCHEMBL7332018 | 0.74 | HRH1 (0.67) | MEN1KMT2AL3MBTL1TSHR | |
| SCHEMBL4565147 | 0.74 | LTB4R (0.54) | MEN1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5508433-A | Derivatives of perhydroisoindole and preparation thereof | RHONE-POULENC RORER S.A. (FR) | 1996-04-16 | — | — | US | disclosed |
| US-5484942-A | Thiopyranopyrrole derivatives | RHONE-POULENC RORER S.A. (FR) | 1996-01-16 | — | — | US | disclosed |
| US-5451601-A | Perhydroisoindole derivatives and pharmaceutical compositions containing them | RHONE-POULENC RORER S.A. (FR) | 1995-09-19 | — | — | US | disclosed |