Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 4/20 | 0.54 |
| ▸ | LTB4R2 | Q9NPC1 | 4/20 | 0.54 |
| ▸ | CXCL8 | P10145 | 2/20 | 0.50 |
| ▸ | CFD | P00746 | 3/20 | 0.49 |
| ▸ | TPSB2 | P20231 | 3/20 | 0.49 |
| ▸ | F11 | P03951 | 2/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.46 |
| ▸ | RORC | P51449 | 2/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4565147 | 1.00 | LTB4R (0.54) | LTB4RLTB4R2CXCL8CFDTPSB2 | |
| SCHEMBL16410220 | 0.86 | CHRM1 (0.52) | LTB4RLTB4R2CXCL8CFDTPSB2 | |
| SCHEMBL23229157 | 0.85 | CXCL8 (0.54) | CXCL8CFDTPSB2F11L3MBTL1 | |
| SCHEMBL3941649 | 0.85 | CXCL8 (0.54) | CXCL8CFDTPSB2F11L3MBTL1 | |
| SCHEMBL9027265 | 0.83 | ADRA2A (0.54) | LTB4RLTB4R2FFAR1L3MBTL1RORC | |
| SCHEMBL7986709 | 0.83 | LTB4R (0.48) | LTB4RLTB4R2CFDTPSB2F11 | |
| SCHEMBL7986710 | 0.83 | LTB4R (0.48) | LTB4RLTB4R2CFDTPSB2F11 | |
| SCHEMBL10922629 | 0.81 | CXCL8 (0.50) | CXCL8CFDTPSB2F11L3MBTL1 | |
| SCHEMBL24200105 | 0.81 | CXCL8 (0.50) | LTB4RLTB4R2CXCL8CFDTPSB2 | |
| SCHEMBL8086435 | 0.81 | CXCL8 (0.50) | LTB4RLTB4R2CXCL8CFDTPSB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7491723-B2 | Alkanol and cycloalkanol-amine derivatives and methods of their use | WYETH (US) | 2009-02-17 | — | — | US | disclosed |
| US-7365076-B2 | Substituted aryl cycloalkanol derivatives and methods of their use | WYETH (US) | 2008-04-29 | — | — | US | disclosed |
| US-20050171115-A1 | Alkanol and cycloalkanol-amine derivatives and methods of their use | WYETH (US) | 2005-08-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050171115-A1 | Alkanol and cycloalkanol-amine derivatives and methods of their use | FAAH, HTR3A, MAOA | LTB4R 471/4885LTB4R2 358/4885CXCL8 1666/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.