SCHEMBL899953

SCHEMBL899953

Nc1cc(F)c(F)c(F)c1N

nearest known ligand 0.36

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.36
LMNA P02545 1/20 0.35
CA12 O43570 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA7 P43166 1/20 0.33
CA13 Q8N1Q1 1/20 0.33
PTK2 Q05397 1/20 0.32
CES2 O00748 1/20 0.31
CES1 P23141 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ether SCHEMBL10417396 0.81
SCHEMBL8919707 0.79 CA1 (0.40) ALDH1A1LMNACA12CA1CA2
SCHEMBL998262 0.79 ALDH1A1 (0.38) ALDH1A1LMNACA12CA1CA2
SCHEMBL1032872 0.79 CA1 (0.40) ALDH1A1LMNACA12CA1CA2
SCHEMBL30952527 0.79 CA1 (0.40) ALDH1A1LMNACA12CA1CA2
SCHEMBL9142584 0.78 ALDH1A1 (0.32) ALDH1A1LMNA
SCHEMBL29690296 0.77 ALDH1A1 (0.36) ALDH1A1LMNACA12CA1CA2
SCHEMBL1462129 0.77 ALDH1A1 (0.36) ALDH1A1LMNACA12CA1CA2
SCHEMBL30688718 0.77 ALDH1A1 (0.36) ALDH1A1CA1CA2PTK2
SCHEMBL5513285 0.77 ALDH1A1 (0.36) ALDH1A1CA1CA2PTK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122011311-A Preparation method of metal nanocluster confined covalent organic framework composite material 西北工业大学 2026-05-12 CN claimed
CN-118185500-A High-frequency low-loss insulating adhesive film and preparation method thereof 福建臻璟新材料科技有限公司 2024-06-14 CN claimed
WO-2003103832-A2 OXYGEN REDUCTION CATALYST UNIVERSITY TECHNOLOGIES INTERNATIONAL INC. (CA) 2003-12-18 WO claimed
US-20030228972-A1 Using cobalt containing coordination catalyst UNIVERSITY TECHNOLOGIES INTERNATIONAL, INC. (CA) 2003-12-11 US claimed
CN-122036621-A Fluorine substituted benzimidazolyl aniline compound and synthetic method and application thereof 中茂绿能科技(西安)有限公司 2026-05-15 CN disclosed
CN-122011311-A Preparation method of metal nanocluster confined covalent organic framework composite material 西北工业大学 2026-05-12 CN disclosed
US-20250331419-A1 COMPOUND, LIGHT EMITTING MATERIAL, AND ORGANIC LIGHT EMITTING DEVICE KYULUX INC (JP) 2025-10-23 US disclosed
CN-119095850-A Compound, light-emitting material, and organic light-emitting element 九州有机光材股份有限公司 2024-12-06 CN disclosed
CN-118185500-A High-frequency low-loss insulating adhesive film and preparation method thereof 福建臻璟新材料科技有限公司 2024-06-14 CN disclosed
US-20240132479-A1 THERAPEUTIC COMPOUNDS AND USES THEREOF BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY 2024-04-25 US disclosed
WO-2023210192-A1 COMPOUND, LIGHT-EMITTING MATERIAL, AND ORGANIC LIGHT-EMITTING DEVICE 株式会社Kyulux 2023-11-02 WO disclosed
WO-2022165198-A1 THERAPEUTIC COMPOUNDS AND USES THEREOF BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) 2022-08-04 WO disclosed
US-5631373-A NERVOUS SYSTEM DISORDERS STATE OF OREGON, ACTING BY AND THROUGH THE OREGON STATE BOARD OF HIGHER EDUCATION, ACTING FOR AND ON BEHALF OF THE OREGON HEALTH SCIENCES UNIVERSITY AND THE UNIVERSITY OF OREGON, EUGENE OREGON (US) 1997-05-20 US disclosed
US-5622952-A NERVOUS SYSTEM DISORDERS; ADMINISTERING 1,4-DIHYDROQUINOXALINE-2,3-DIONE STATE OF OREGON, ACTING BY AND THROUGH THE OREGON STATE BOARD OF HIGHER EDUCATION, ACTING FOR AND ON BEHALF OF THE OREGON HEALTH SCIENCES UNIVERSITY AND THE UNIVERSITY OF OREGON, EUGENE OREGON (US) 1997-04-22 US disclosed
US-5620979-A TREATING NEURONAL LOSS ASSOCIATED WITH STROKE, ISCHEMIA, CENTRAL NERVOUS SYSTEM TRAUMA, HYPOGLYCEMIA OR SURGERY STATE OF OREGON, ACTING BY AND THROUGH THE OREGON STATE BOARD OF HIGHER EDUCATION, ACTING FOR AND ON BEHALF OF THE OREGON HEALTH SCIENCES UNIVERSITY AND THE UNIVERSITY OF OREGON, EUGENE OREGON (US) 1997-04-15 US disclosed
EP-0732942-A1 ALKYL, AZIDO, ALKOXY, AND FLUORO-SUBSTITUTED AND FUSED QUINOXALINEDIONES AND THE USE THEREOF AS GLYCINE RECEPTOR ANTAGONISTS ACEA PHARMACEUTICALS, INC. (US) 1996-09-25 EP disclosed
US-5514680-A ANTICONVULSANTS WITH 5,6,7-TRISUBSTITUTED-1,4-DIHYDROQUINOXALINE-2,3-DIONE THE STATE OF OREGON, ACTING BY AND THROUGH THE OREGON STATE BOARD OF HIGHER EDUCATION, ACTING FOR AND ON BEHALF OF THE OREGON HEALTH SCIENCES UNIVERSITY (US) 1996-05-07 US disclosed
US-5449584-A Positive photo-sensitive resin composition comprising a photosensitive polybenzoxazole or a mixture of a polybenzoxazole, an organic solvent soluble polymer and a diazoquinone and/or a dihydropyridine compound SUMITOMO BAKELITE COMPANY, LTD. (JP) 1995-09-12 US disclosed
WO-1995012417-A1 ALKYL, AZIDO, ALKOXY, AND FLUORO-SUBSTITUTED AND FUSED QUINOXALINEDIONES AND THE USE THEREOF AS GLYCINE RECEPTOR ANTAGONISTS ACEA PHARMACEUTICALS, INC. (US) 1995-05-11 WO disclosed
EP-0459395-A2 Positive photo-sensitive resin composition SUMITOMO BAKELITE COMPANY LIMITED (JP) 1991-12-04 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240132479-A1 THERAPEUTIC COMPOUNDS AND USES THEREOF CUTA, DCXR, PLOD3 ALDH1A1 349/4885LMNA 555/4885CA12 4194/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.