Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.46 |
| ▸ | RXRA | P19793 | 6/20 | 0.45 |
| ▸ | RXRB | P28702 | 6/20 | 0.45 |
| ▸ | RXRG | P48443 | 5/20 | 0.45 |
| ▸ | KDM1A | O60341 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.40 |
| ▸ | BCR | P11274 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 2/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | HSD17B13 | Q7Z5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29319988 | 0.92 | RXRA (0.48) | KIF11RXRARXRBRXRGKDM1A | |
| SCHEMBL17204158 | 0.87 | KIF11 (0.54) | KIF11RXRARXRBRXRGKDM1A | |
| SCHEMBL69029 | 0.86 | PTGS1 (0.52) | KIF11KDM1APTGS1CES2GABRA1 | |
| SCHEMBL186842 | 0.86 | GABRA1 (0.52) | KIF11RXRARXRBRXRGPTGS1 | |
| SCHEMBL21944981 | 0.84 | CA12 (0.48) | KIF11RXRARXRBRXRGKDM1A | |
| SCHEMBL29319890 | 0.84 | RXRA (0.50) | KIF11RXRARXRBRXRGKDM1A | |
| SCHEMBL21945058 | 0.84 | CYP11B2 (0.45) | RXRARXRBRXRGKDM1A | |
| SCHEMBL29886876 | 0.83 | CES2 (0.56) | KIF11RXRARXRBRXRGPTGS1 | |
| SCHEMBL29384937 | 0.83 | GABRA1 (0.50) | KIF11RXRARXRBRXRGPTGS1 | |
| Water SCHEMBL21493255 | 0.83 | GABRA1 (0.50) | KIF11RXRARXRBRXRGPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5578697-A | DIELECTRIC POLYMERS FOR ELECTRONICS | KABUSHIKI KAISHA TOSHIBA (JP) | 1996-11-26 | — | — | US | disclosed |