Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 10/20 | 0.38 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.33 |
| ▸ | AR | P10275 | 2/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.33 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8999916 | 0.80 | CYP19A1 (0.38) | CYP19A1 | |
| SCHEMBL8999935 | 0.79 | CYP19A1 (0.36) | CYP19A1 | |
| SCHEMBL8999941 | 0.78 | CYP19A1 (0.35) | CYP19A1NR3C1ARPGRNR3C2 | |
| SCHEMBL10942311 | 0.69 | CYP19A1 (0.42) | CYP19A1NR3C1 | |
| SCHEMBL8999931 | 0.65 | CYP19A1 (0.67) | CYP19A1NR3C1CYP17A1 | |
| SCHEMBL1401929 | 0.62 | CYP19A1 (0.40) | CYP19A1NR3C1 | |
| SCHEMBL8020260 | 0.62 | CYP19A1 (0.40) | CYP19A1NR3C1 | |
| SCHEMBL10582213 | 0.62 | NR3C1 (0.41) | CYP19A1NR3C1ARPGRNR3C2 | |
| SCHEMBL9622893 | 0.62 | NR3C1 (0.41) | CYP19A1NR3C1ARPGRNR3C2 | |
| SCHEMBL2118371 | 0.60 | NR3C1 (0.64) | CYP19A1NR3C1ARPGRCYP17A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0515264-B1 | New steroid derivatives of pregna-4,9(11),17(20)-trien-3-on, their preparation, their use in the preparation of derivatives of pregna-4,9(11),16-trien-3,20-dione and intermediates therefor | ROUSSEL UCLAF (FR) | 1996-09-11 | — | — | EP | disclosed |
| EP-0515264-A2 | New steroid derivatives of pregna-4,9(11),17(20)-trien-3-on, their preparation, their use in the preparation of derivatives of pregna-4,9(11),16-trien-3,20-dione and intermediates therefor | ROUSSEL UCLAF (FR) | 1992-11-25 | — | — | EP | disclosed |