Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 5/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | CMA1 | P23946 | 1/20 | 0.33 |
| ▸ | AHR | P35869 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | MIF | P14174 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | HBB | P68871 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8973600 | 0.90 | CA2 (0.43) | CA2MEN1KMT2ACA12CA1 | |
| SCHEMBL8800132 | 0.83 | CA2 (0.49) | MAOBCA2MEN1KMT2ACA12 | |
| SCHEMBL8799877 | 0.79 | MEN1 (0.33) | MEN1KMT2AMAPTALDH1A1POLB | |
| SCHEMBL8800240 | 0.77 | AKR1B1 (0.47) | MAOBCA2MEN1KMT2ACA12 | |
| SCHEMBL8798817 | 0.76 | TERT (0.34) | CA2MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL9000112 | 0.76 | MEN1 (0.36) | MEN1KMT2AMMP2CMA1AHR | |
| SCHEMBL8973637 | 0.76 | MMP2 (0.46) | MEN1KMT2AMMP2MAPTALDH1A1 | |
| SCHEMBL8799255 | 0.72 | CA2 (0.46) | CA2MEN1KMT2ACA12CA1 | |
| SCHEMBL8799930 | 0.71 | MEN1 (0.35) | MEN1KMT2AAHRMAPTALDH1A1 | |
| SCHEMBL8798983 | 0.71 | ALDH1A1 (0.33) | MEN1KMT2AMAPTALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0444546-B1 | Hydantoin derivatives for use as hypoglycemic and/or hypolipidemic agents | MOCHIDA PHARM CO LTD (JP) | 1996-09-11 | — | — | EP | disclosed |
| US-5202339-A | Hypoglycemic, hypolipedemic agents | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1993-04-13 | — | — | US | disclosed |
| WO-1991012803-A1 | HYDANTOIN DERIVATIVES FOR USE AS HYPOGLYCEMIC AND/OR HYPOLIPIDEMIC AGENTS | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1991-09-05 | — | — | WO | disclosed |
| EP-0444546-A1 | Hydantoin derivatives for use as hypoglycemic and/or hypolipidemic agents | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1991-09-04 | — | — | EP | disclosed |