Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 7/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | GHSR | Q92847 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9002031 | 0.96 | ACHE (0.34) | ACHETDP1HRH3ALDH1A1HPGD | |
| SCHEMBL9002520 | 0.89 | ACHE (0.43) | ACHEHPGDPOLBEPHX2 | |
| SCHEMBL9001983 | 0.84 | ALDH1A1 (0.52) | TDP1ALDH1A1HPGDHSD17B10 | |
| SCHEMBL9002724 | 0.83 | KDM4E (0.45) | ALDH1A1POLB | |
| SCHEMBL9002366 | 0.82 | ACHE (0.39) | ACHEALDH1A1HPGDEPHX2 | |
| SCHEMBL9001857 | 0.82 | HPGD (0.34) | ACHEHPGDPOLBEPHX2 | |
| SCHEMBL9002395 | 0.82 | LMNA (0.34) | ALDH1A1HSD17B10POLB | |
| SCHEMBL9002205 | 0.81 | ALDH1A1 (0.39) | TDP1ALDH1A1HPGD | |
| SCHEMBL9002225 | 0.80 | PKM (0.40) | ALDH1A1 | |
| SCHEMBL9001998 | 0.80 | SMN1; SMN2 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5587383-A | CALMODULIN INHIBITORS; ANTIISCHEMIC AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-12-24 | — | — | US | disclosed |
| EP-0471236-B1 | Imidazopyridine derivatives and their use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1995-03-15 | — | — | EP | disclosed |
| US-5395839-A | Calmodulin and angiogenesis inhibitors | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1995-03-07 | — | — | US | disclosed |
| EP-0471236-A1 | Imidazopyridine derivatives and their use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1992-02-19 | — | — | EP | disclosed |