Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.34 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8956402 | 0.85 | NPC1 (0.38) | LMNAALDH1A1SMN1; SMN2TDP1KMT2A | |
| SCHEMBL9003692 | 0.72 | PTGS2 (0.33) | — | |
| SCHEMBL29227275 | 0.67 | L3MBTL1 (0.46) | LMNAALDH1A1TDP1KMT2AMAPT | |
| SCHEMBL16886108 | 0.66 | EGFR (0.47) | LMNAALDH1A1HTTSMN1; SMN2TDP1 | |
| SCHEMBL14698829 | 0.66 | EGFR (0.47) | LMNAALDH1A1HTTSMN1; SMN2TDP1 | |
| SCHEMBL28354801 | 0.64 | APP (0.42) | LMNAALDH1A1HTTSMN1; SMN2TDP1 | |
| SCHEMBL9069194 | 0.64 | ALDH1A1 (0.42) | LMNAALDH1A1HTTSMN1; SMN2TDP1 | |
| SCHEMBL9456794 | 0.64 | CES2 (0.42) | LMNAALDH1A1HTTSMN1; SMN2TDP1 | |
| SCHEMBL6116313 | 0.63 | ACHE (0.68) | LMNAALDH1A1SMN1; SMN2TDP1ACHE | |
| SCHEMBL6116896 | 0.63 | ACHE (0.68) | LMNAALDH1A1SMN1; SMN2TDP1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5500453-A | INITIATOR FOR PHOTOSENSITIVE FREE RADICAL CURING/ POLYMERIZATION OF UNSATURATED COMPOUNDS | TOYO INK MANUFACTURING CO., LTD. (JP) | 1996-03-19 | — | — | US | disclosed |