SCHEMBL9003382

SCHEMBL9003382

C=CC(S)(c1ccc(C(C)(C)C)cc1)c1ccc(C(C)(C)C)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.44
LMNA P02545 1/20 0.42
TYR P14679 1/20 0.42
ALDH1A1 P00352 5/20 0.38
HPGD P15428 2/20 0.38
ALOX15 P16050 1/20 0.38
HSD17B10 Q99714 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
BCHE P06276 3/20 0.37
ACHE P22303 3/20 0.37
KIF11 P52732 2/20 0.37
CYP1A2 P05177 1/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
CA9 Q16790 1/20 0.36
MAPT P10636 2/20 0.34
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
NPC1 O15118 1/20 0.34
MAPK1 P28482 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9003458 0.76 MEN1 (0.39) TSHRLMNAKIF11MEN1KMT2A
SCHEMBL9858671 0.75 TSHR (0.48) TSHRLMNATYRALDH1A1HPGD
SCHEMBL2326872 0.75 TSHR (0.38) TSHRALDH1A1KIF11CYP1A2CA1
SCHEMBL16312983 0.74 KIF11 (0.44) TSHRLMNAALDH1A1HPGDACHE
SCHEMBL424728 0.72 TSHR (0.73) TSHRLMNATYRALDH1A1HPGD
SCHEMBL807575 0.71 TSHR (0.55) TSHRLMNATYRALDH1A1HPGD
SCHEMBL15198 0.70 ALDH1A1 (0.58) TSHRLMNATYRALDH1A1TDP1
Hydrogen Sulfide SCHEMBL29029008 0.68 ALDH1A1 (0.55) TSHRLMNATYRALDH1A1TDP1
SCHEMBL9003476 0.67 ALDH1A1 (0.41) TSHRLMNATYRALDH1A1HPGD
Butadiene SCHEMBL4270330 0.67 ALDH1A1 (0.52) TSHRLMNATYRALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5500453-A INITIATOR FOR PHOTOSENSITIVE FREE RADICAL CURING/ POLYMERIZATION OF UNSATURATED COMPOUNDS TOYO INK MANUFACTURING CO., LTD. (JP) 1996-03-19 US disclosed