SCHEMBL9858671

SCHEMBL9858671

C=CC(C)(C)c1ccc(C(C)(C)C)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.48
LMNA P02545 1/20 0.46
TYR P14679 1/20 0.46
ALDH1A1 P00352 5/20 0.40
BCHE P06276 5/20 0.39
ACHE P22303 5/20 0.39
KIF11 P52732 2/20 0.39
CYP1A2 P05177 1/20 0.39
HPGD P15428 2/20 0.37
NPC1 O15118 1/20 0.37
MAPT P10636 1/20 0.37
MAPK1 P28482 1/20 0.37
RAB9A P51151 1/20 0.37
HDAC1 Q13547 1/20 0.37
SLC22A2 O15244 1/20 0.37
SLC22A1 O15245 1/20 0.37
SLC22A3 O75751 1/20 0.37
MEN1 O00255 1/20 0.36
HTT P42858 1/20 0.36
KMT2A Q03164 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9858415 0.82 TSHR (0.52) TSHRALDH1A1ACHEKIF11HPGD
SCHEMBL5682958 0.82
SCHEMBL24278474 0.80 RAB9A (0.37) ALDH1A1ACHENPC1MAPTMAPK1
SCHEMBL9790116 0.80 ESR1 (0.54) TSHRLMNATYRALDH1A1KIF11
SCHEMBL24277963 0.80 TGM2 (0.41) TSHRALDH1A1KIF11CYP1A2
SCHEMBL737574 0.79 MAPK1 (0.44) TSHRALDH1A1MAPTMAPK1HDAC1
SCHEMBL424728 0.76 TSHR (0.73) TSHRLMNATYRALDH1A1BCHE
SCHEMBL4926591 0.76 TSHR (0.50) TSHRLMNATYRALDH1A1BCHE
SCHEMBL23747059 0.75 KIF11 (0.41) TSHRLMNAALDH1A1KIF11HPGD
SCHEMBL9003382 0.75 TSHR (0.44) TSHRLMNATYRALDH1A1BCHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0291849-B1 4-METHYL-4-PHENYL-PENTAN-1-ALS, THEIR PREPARATION AND APPLICATION AS AROMA CHEMICALS BASF Aktiengesellschaft (DE) 1991-10-16 EP disclosed
US-4837201-A 4-Methyl-4-phenyl-1-pentanals, their preparation and their use as scents BASF AKTIENGESELLSCHAFT (DE) 1989-06-06 US disclosed
EP-0291849-A2 4-Methyl-4-phenyl-pentan-1-als, their preparation and application as aroma chemicals BASF Aktiengesellschaft (DE) 1988-11-23 EP disclosed