Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 13/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.42 |
| ▸ | HRH1 | P35367 | 2/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.42 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9004097 | 0.93 | LTA4H (0.41) | HRH3CHRM1HTR2AMCHR1 | |
| SCHEMBL9004134 | 0.88 | CHRM1 (0.41) | HRH3SLC6A2CHRM2SLC6A4SLC6A3 | |
| SCHEMBL9004099 | 0.88 | HRH3 (0.43) | HRH3SLC6A2HRH1CHRM2ADRA2C | |
| SCHEMBL9412241 | 0.88 | HRH3 (0.43) | HRH3SLC6A2HRH1CHRM2ADRA2C | |
| SCHEMBL9004074 | 0.87 | HRH3 (0.41) | HRH3SLC6A2HRH1CHRM2ADRA2C | |
| SCHEMBL9004110 | 0.84 | HSP90AA1 (0.50) | HRH3HRH1KCNH2MAOB | |
| SCHEMBL9004176 | 0.81 | CHRM1 (0.39) | HRH3SLC6A2CHRM2SLC6A4SLC6A3 | |
| SCHEMBL9004170 | 0.78 | KEAP1 (0.43) | HRH3KMT2A | |
| SCHEMBL9004061 | 0.78 | HRH3 (0.43) | HRH3SLC6A4MAOBMEN1KMT2A | |
| SCHEMBL6548852 | 0.72 | HSP90AA1 (0.51) | HRH3HRH1CHRM2KCNH2CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5486528-A | ANTIULCER AGENTS, ANXIOLYTIC AGENTS | EGIS GYOGYSZERGYAR RT. (HU) | 1996-01-23 | — | — | US | disclosed |