Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 13/20 | 0.40 |
| ▸ | THRA | P10827 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9004060 | 0.93 | HRH3 (0.44) | HRH3CHRM1HTR2AMCHR1 | |
| SCHEMBL9004134 | 0.92 | CHRM1 (0.41) | LTA4HHRH3CHRM1HTR2AMCHR1 | |
| SCHEMBL9004176 | 0.84 | CHRM1 (0.39) | LTA4HHRH3CHRM1HTR2AMCHR1 | |
| SCHEMBL9004099 | 0.83 | HRH3 (0.43) | HRH3CHRM1HTR2AMCHR1 | |
| SCHEMBL9412241 | 0.83 | HRH3 (0.43) | HRH3CHRM1HTR2AMCHR1 | |
| SCHEMBL9004074 | 0.82 | HRH3 (0.41) | HRH3 | |
| SCHEMBL9004110 | 0.79 | HSP90AA1 (0.50) | LTA4HHRH3KDM4E | |
| SCHEMBL9004116 | 0.73 | TRPA1 (0.56) | KDM4E | |
| SCHEMBL9004170 | 0.73 | KEAP1 (0.43) | HRH3KDM4EGAA | |
| SCHEMBL9004061 | 0.73 | HRH3 (0.43) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5486528-A | ANTIULCER AGENTS, ANXIOLYTIC AGENTS | EGIS GYOGYSZERGYAR RT. (HU) | 1996-01-23 | — | — | US | claimed |
| US-5486528-A | ANTIULCER AGENTS, ANXIOLYTIC AGENTS | EGIS GYOGYSZERGYAR RT. (HU) | 1996-01-23 | — | — | US | disclosed |
| EP-0619299-A2 | 1-(Phenyl)-3-[omega-(amino)-alkoxyimino]-alk-1-ene derivatives, a process for preparing them as well as medicaments containing them and the use of them | EGIS GYOGYSZERGYAR RT. (HU) | 1994-10-12 | — | — | EP | disclosed |