Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.45 |
| ▸ | RARB | P10826 | 6/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.42 |
| ▸ | RARA | P10276 | 1/20 | 0.42 |
| ▸ | MTOR | P42345 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11202170 | 0.86 | PLAU (0.44) | CA2FOLH1MEN1ALDH1A1MAPT | |
| SCHEMBL29432860 | 0.85 | ALDH1A1 (0.52) | CA2FOLH1MEN1ALDH1A1MAPT | |
| SCHEMBL859719 | 0.85 | ALDH1A1 (0.52) | CA2FOLH1MEN1ALDH1A1MAPT | |
| SCHEMBL11205359 | 0.84 | MMP2 (0.48) | CA2FOLH1TSHRMEN1ALDH1A1 | |
| SCHEMBL31572043 | 0.84 | RARB (0.46) | RARBTP53TSHRMEN1ALDH1A1 | |
| SCHEMBL660558 | 0.83 | HTT (0.47) | TP53TSHRMEN1ALDH1A1MAPT | |
| SCHEMBL15697950 | 0.83 | HTT (0.47) | TP53TSHRMEN1ALDH1A1MAPT | |
| SCHEMBL15671510 | 0.82 | FPR2 (0.45) | CA2FOLH1TSHRMEN1ALDH1A1 | |
| SCHEMBL5339629 | 0.82 | TAS1R3 (0.50) | MEN1ALDH1A1MAPTKMT2AMAPK1 | |
| SCHEMBL15199285 | 0.81 | HSD17B3 (0.54) | FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0733037-A1 | ARYL SUBSTITUTED AMINO ACIDS, CNS INFLUENCING AGENTS | UNIVERSITY OF BRISTOL (GB) | 1996-09-25 | — | — | EP | disclosed |
| WO-1995015941-A1 | ARYL SUBSTITUTED AMINO ACIDS, CNS INFLUENCING AGENTS | UNIVERSITY OF BRISTOL (GB) | 1995-06-15 | — | — | WO | disclosed |