Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 9/20 | 0.70 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | NOS3 | P29474 | 2/20 | 0.41 |
| ▸ | NOS1 | P29475 | 2/20 | 0.41 |
| ▸ | NOS2 | P35228 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9004146 | 0.85 | TRPA1 (0.50) | TRPA1MEN1KMT2ALMNANOS3 | |
| SCHEMBL9004114 | 0.85 | TRPA1 (0.50) | TRPA1MEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL9004173 | 0.84 | ALOX15 (0.50) | TRPA1LMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL1499452 | 0.83 | TRPA1 (1.00) | TRPA1MEN1KMT2AHSD11B1LMNA | |
| SCHEMBL1499454 | 0.83 | TRPA1 (1.00) | TRPA1MEN1KMT2AHSD11B1LMNA | |
| SCHEMBL4452015 | 0.83 | TRPA1 (1.00) | TRPA1MEN1KMT2AHSD11B1LMNA | |
| SCHEMBL9004131 | 0.82 | LMNA (0.56) | TRPA1LMNASMN1; SMN2 | |
| SCHEMBL4450935 | 0.80 | TRPA1 (0.82) | TRPA1HSD11B1LMNAHPGDTNFRSF1A | |
| SCHEMBL4450932 | 0.80 | TRPA1 (0.82) | TRPA1HSD11B1LMNAHPGDTNFRSF1A | |
| SCHEMBL4450936 | 0.80 | TRPA1 (0.82) | TRPA1HSD11B1LMNAHPGDTNFRSF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5486528-A | ANTIULCER AGENTS, ANXIOLYTIC AGENTS | EGIS GYOGYSZERGYAR RT. (HU) | 1996-01-23 | — | — | US | disclosed |
| EP-0619299-A2 | 1-(Phenyl)-3-[omega-(amino)-alkoxyimino]-alk-1-ene derivatives, a process for preparing them as well as medicaments containing them and the use of them | EGIS GYOGYSZERGYAR RT. (HU) | 1994-10-12 | — | — | EP | disclosed |