Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | TNKS | O95271 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9004118 | 0.94 | TRPA1 (0.58) | ALOX15TRPA1TDP1GLAALDH1A1 | |
| SCHEMBL9004146 | 0.84 | TRPA1 (0.50) | TRPA1ALDH1A1CYP1A2SMN1; SMN2HDAC2 | |
| SCHEMBL9004114 | 0.84 | TRPA1 (0.50) | TRPA1TDP1ALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL9004073 | 0.84 | TRPA1 (0.70) | TRPA1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL9004180 | 0.83 | ALOX15 (0.53) | ALOX15TRPA1TDP1GLAALDH1A1 | |
| SCHEMBL9004179 | 0.83 | ALOX15 (0.53) | ALOX15TRPA1TDP1GLAALDH1A1 | |
| SCHEMBL9004124 | 0.83 | ALOX15 (0.53) | ALOX15TRPA1TDP1GLAALDH1A1 | |
| SCHEMBL9004131 | 0.82 | LMNA (0.56) | TRPA1TDP1SMN1; SMN2HDAC3HDAC1 | |
| SCHEMBL9004187 | 0.81 | TRPA1 (0.71) | ALOX15TRPA1TDP1GLAALDH1A1 | |
| SCHEMBL9004165 | 0.78 | NOS2 (0.44) | TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5486528-A | ANTIULCER AGENTS, ANXIOLYTIC AGENTS | EGIS GYOGYSZERGYAR RT. (HU) | 1996-01-23 | — | — | US | disclosed |
| EP-0619299-A2 | 1-(Phenyl)-3-[omega-(amino)-alkoxyimino]-alk-1-ene derivatives, a process for preparing them as well as medicaments containing them and the use of them | EGIS GYOGYSZERGYAR RT. (HU) | 1994-10-12 | — | — | EP | disclosed |