Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | NOS3 | P29474 | 2/20 | 0.37 |
| ▸ | NOS1 | P29475 | 2/20 | 0.37 |
| ▸ | NOS2 | P35228 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 2/20 | 0.35 |
| ▸ | UTS2R | Q9UKP6 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9004119 | 0.88 | MAOB (0.39) | MEN1KMT2ATRPA1LMNAALDH1A1 | |
| SCHEMBL9004100 | 0.80 | HTR2A (0.46) | MAPTMEN1KMT2ATRPA1LMNA | |
| SCHEMBL9004091 | 0.79 | LMNA (0.45) | MAPTNOS3NOS1NOS2LMNA | |
| SCHEMBL9004140 | 0.78 | LMNA (0.44) | MAPTNOS3NOS1NOS2LMNA | |
| SCHEMBL9004183 | 0.76 | NFE2L2 (0.43) | MAPTMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL9004142 | 0.74 | KCNH2 (0.42) | MAPTMEN1KMT2ATRPA1LMNA | |
| SCHEMBL9412273 | 0.73 | HTR2A (0.43) | MAPTNOS3NOS1NOS2LMNA | |
| SCHEMBL9004133 | 0.73 | ALOX15 (0.45) | MAPTMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL9004144 | 0.71 | UTS2R (0.39) | MAPTNOS3NOS1NOS2LMNA | |
| SCHEMBL9004115 | 0.71 | HTR2A (0.45) | MAPTMEN1KMT2ATRPA1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5486528-A | ANTIULCER AGENTS, ANXIOLYTIC AGENTS | EGIS GYOGYSZERGYAR RT. (HU) | 1996-01-23 | — | — | US | disclosed |
| EP-0619299-A2 | 1-(Phenyl)-3-[omega-(amino)-alkoxyimino]-alk-1-ene derivatives, a process for preparing them as well as medicaments containing them and the use of them | EGIS GYOGYSZERGYAR RT. (HU) | 1994-10-12 | — | — | EP | disclosed |