Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.37 |
| ▸ | MAOB | P27338 | 3/20 | 0.34 |
| ▸ | NOS3 | P29474 | 2/20 | 0.34 |
| ▸ | NOS1 | P29475 | 2/20 | 0.34 |
| ▸ | NOS2 | P35228 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.31 |
| ▸ | TUBB | P07437 | 2/20 | 0.31 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.31 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.31 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.31 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9004140 | 0.86 | LMNA (0.44) | KCNH2NOS3NOS1NOS2MAPT | |
| SCHEMBL9004070 | 0.85 | HSF1 (0.39) | NOS3NOS1NOS2MAPTTRPA1 | |
| SCHEMBL9412212 | 0.83 | NOS3 (0.37) | NOS3NOS1NOS2MAPTMEN1 | |
| SCHEMBL9004137 | 0.79 | POLB (0.44) | MEN1KMT2AGAAHTTCYP1A2 | |
| SCHEMBL9004091 | 0.76 | LMNA (0.45) | KCNH2NOS3NOS1NOS2MAPT | |
| SCHEMBL9004144 | 0.75 | UTS2R (0.39) | NOS3NOS1NOS2MAPTLMNA | |
| SCHEMBL9004096 | 0.75 | ACHE (0.38) | KCNH2MAOBNOS3NOS1NOS2 | |
| SCHEMBL9412273 | 0.75 | HTR2A (0.43) | MAOBNOS3NOS1NOS2MAPT | |
| SCHEMBL9004074 | 0.72 | HRH3 (0.41) | KCNH2MAOBMEN1KMT2A | |
| SCHEMBL9004099 | 0.71 | HRH3 (0.43) | KCNH2MAOBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5486528-A | ANTIULCER AGENTS, ANXIOLYTIC AGENTS | EGIS GYOGYSZERGYAR RT. (HU) | 1996-01-23 | — | — | US | disclosed |
| EP-0619299-A2 | 1-(Phenyl)-3-[omega-(amino)-alkoxyimino]-alk-1-ene derivatives, a process for preparing them as well as medicaments containing them and the use of them | EGIS GYOGYSZERGYAR RT. (HU) | 1994-10-12 | — | — | EP | disclosed |