Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSF1 | Q00613 | 1/20 | 0.39 |
| ▸ | NOS3 | P29474 | 2/20 | 0.35 |
| ▸ | NOS1 | P29475 | 2/20 | 0.35 |
| ▸ | NOS2 | P35228 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 6/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9004140 | 0.90 | LMNA (0.44) | NOS3NOS1NOS2LMNAMAPT | |
| SCHEMBL9004128 | 0.85 | KCNH2 (0.37) | NOS3NOS1NOS2LMNAMAPT | |
| SCHEMBL9412212 | 0.85 | NOS3 (0.37) | NOS3NOS1NOS2LMNAMAPT | |
| SCHEMBL9004137 | 0.81 | POLB (0.44) | HSF1SMN1; SMN2HTTNPC1RAB9A | |
| SCHEMBL9004091 | 0.80 | LMNA (0.45) | NOS3NOS1NOS2LMNAMAPT | |
| SCHEMBL9412273 | 0.79 | HTR2A (0.43) | NOS3NOS1NOS2LMNAMAPT | |
| SCHEMBL9004191 | 0.78 | KMT2A (0.37) | LMNAMAPTSMN1; SMN2HTTALDH1A1 | |
| SCHEMBL9004146 | 0.77 | TRPA1 (0.50) | NOS3NOS1NOS2LMNAMAPT | |
| SCHEMBL9004096 | 0.77 | ACHE (0.38) | NOS3NOS1NOS2LMNAMAPT | |
| SCHEMBL9004144 | 0.77 | UTS2R (0.39) | NOS3NOS1NOS2LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5486528-A | ANTIULCER AGENTS, ANXIOLYTIC AGENTS | EGIS GYOGYSZERGYAR RT. (HU) | 1996-01-23 | — | — | US | disclosed |
| EP-0619299-A2 | 1-(Phenyl)-3-[omega-(amino)-alkoxyimino]-alk-1-ene derivatives, a process for preparing them as well as medicaments containing them and the use of them | EGIS GYOGYSZERGYAR RT. (HU) | 1994-10-12 | — | — | EP | disclosed |