Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | CDK4 | P11802 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | NOS3 | P29474 | 2/20 | 0.36 |
| ▸ | NOS1 | P29475 | 2/20 | 0.36 |
| ▸ | NOS2 | P35228 | 2/20 | 0.36 |
| ▸ | CDK2 | P24941 | 3/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.34 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9004140 | 0.90 | LMNA (0.44) | LMNASMN1; SMN2CDK4MAPTALDH1A1 | |
| SCHEMBL9004070 | 0.80 | HSF1 (0.39) | LMNASMN1; SMN2MAPTALDH1A1NPC1 | |
| SCHEMBL9004068 | 0.79 | MAPT (0.38) | LMNASMN1; SMN2MAPTALDH1A1NPC1 | |
| SCHEMBL9004128 | 0.76 | KCNH2 (0.37) | LMNAMAPTHTTNOS3NOS1 | |
| SCHEMBL9412212 | 0.76 | NOS3 (0.37) | LMNASMN1; SMN2MAPTALDH1A1NPC1 | |
| SCHEMBL9412273 | 0.74 | HTR2A (0.43) | LMNASMN1; SMN2MAPTALDH1A1NPC1 | |
| SCHEMBL9004043 | 0.73 | TDP1 (0.43) | LMNASMN1; SMN2CDK4NPC1RAB9A | |
| SCHEMBL9004042 | 0.73 | TRPA1 (0.47) | LMNASMN1; SMN2MAPTALDH1A1NPC1 | |
| SCHEMBL9004144 | 0.72 | UTS2R (0.39) | LMNASMN1; SMN2MAPTALDH1A1NPC1 | |
| SCHEMBL9004137 | 0.72 | POLB (0.44) | SMN1; SMN2NPC1HTTRAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5486528-A | ANTIULCER AGENTS, ANXIOLYTIC AGENTS | EGIS GYOGYSZERGYAR RT. (HU) | 1996-01-23 | — | — | US | disclosed |
| EP-0619299-A2 | 1-(Phenyl)-3-[omega-(amino)-alkoxyimino]-alk-1-ene derivatives, a process for preparing them as well as medicaments containing them and the use of them | EGIS GYOGYSZERGYAR RT. (HU) | 1994-10-12 | — | — | EP | disclosed |