Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | PRMT5 | O14744 | 9/20 | 0.36 |
| ▸ | WDR77 | Q9BQA1 | 9/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | HTR1D | P28221 | 1/20 | 0.34 |
| ▸ | HTR1B | P28222 | 1/20 | 0.34 |
| ▸ | GRM5 | P41594 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8640678 | 0.87 | LMNA (0.39) | LMNAMAPTPRMT5WDR77ALDH1A1 | |
| SCHEMBL9004558 | 0.83 | LMNA (0.41) | LMNAMAPTPRMT5WDR77ELANE | |
| SCHEMBL8640666 | 0.83 | ACHE (0.42) | — | |
| SCHEMBL9171923 | 0.82 | ROCK2 (0.44) | MAPTALDH1A1KDM4EHPGDMEN1 | |
| SCHEMBL8981074 | 0.79 | LMNA (0.39) | LMNAMAPTPRMT5WDR77ALDH1A1 | |
| SCHEMBL9174102 | 0.76 | CYP19A1 (0.39) | MEN1KMT2ACYP2C9 | |
| SCHEMBL8643444 | 0.76 | MAOB (0.44) | ALDH1A1KDM4E | |
| SCHEMBL9169246 | 0.74 | MAOB (0.38) | — | |
| SCHEMBL8658972 | 0.73 | SMN1; SMN2 (0.39) | LMNAMAPTALDH1A1KDM4EMEN1 | |
| SCHEMBL8576909 | 0.72 | ROCK2 (0.44) | LMNAMAPTALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5480882-A | Benzoxazinone and benzothiazinone derivatives having cardiovascular activity | ITALFARMACO S.P.A. (IT) | 1996-01-02 | — | — | US | disclosed |