Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | HTR3E | A5X5Y0 | 3/20 | 0.50 |
| ▸ | HTR3B | O95264 | 3/20 | 0.50 |
| ▸ | HTR3A | P46098 | 3/20 | 0.50 |
| ▸ | HTR3D | Q70Z44 | 3/20 | 0.50 |
| ▸ | HTR3C | Q8WXA8 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24151316 | 0.77 | ALOX5 (0.43) | KMT2AHTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL7382691 | 0.73 | HTR3E (0.70) | KMT2AHTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL23777613 | 0.72 | ALDH1A1 (0.50) | KMT2AHTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL23777615 | 0.72 | ALDH1A1 (0.50) | KMT2AHTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL10846355 | 0.69 | HTR3E (0.44) | KMT2AHTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL29668691 | 0.68 | HTR3E (0.56) | KMT2AHTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL9213161 | 0.68 | HTR3E (0.56) | KMT2AHTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL7389337 | 0.68 | HTR3E (0.82) | KMT2AHTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL25384299 | 0.67 | GAA (0.44) | KMT2AHTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL25385150 | 0.67 | GAA (0.44) | KMT2AHTR3EHTR3BHTR3AHTR3D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5576320-A | 1-heteruarylazetidines and -pyrrolidines, process for their preparation and pharmaceutical compositions containing them | SANOFI (FR) | 1996-11-19 | — | — | US | disclosed |
| US-5565474-A | 1-heteroarylazetidines and -pyrrolidines process for their preparation and pharmaceutical compositions containing them | SANOFI (FR) | 1996-10-15 | — | — | US | disclosed |