SCHEMBL9005802

SCHEMBL9005802

CCCCNC(=O)c1cc(=O)[nH][nH]1

nearest known ligand 0.61

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 3/20 0.61
DRD2 P14416 1/20 0.51
DRD3 P35462 1/20 0.51
SMN1; SMN2 Q16637 1/20 0.50
KDM4E B2RXH2 3/20 0.49
TSHR P16473 1/20 0.49
HTT P42858 1/20 0.49
ALOX15 P16050 2/20 0.48
ALDH1A1 P00352 2/20 0.46
MAPT P10636 1/20 0.46
PLA2G7 Q13093 1/20 0.44
HPGD P15428 1/20 0.43
ALOX5 P09917 1/20 0.42
NAAA Q02083 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14811748 0.72 TSHR (0.71) DRD2DRD3SMN1; SMN2TSHRHTT
SCHEMBL2914113 0.72 SMN1; SMN2 (0.79) SMN1; SMN2TSHRHTTALDH1A1HPGD
SCHEMBL162430 0.72 DRD2 (0.50) GPR84DRD2DRD3SMN1; SMN2KDM4E
SCHEMBL10244791 0.71 HDAC3 (0.61) DRD2DRD3SMN1; SMN2KDM4ETSHR
SCHEMBL20991401 0.69 SMN1; SMN2 (0.73) SMN1; SMN2KDM4ETSHRHTTALDH1A1
SCHEMBL28253741 0.69 HDAC3 (0.68) GPR84DRD2DRD3SMN1; SMN2KDM4E
SCHEMBL28326194 0.69 L3MBTL1 (0.73) DRD2DRD3SMN1; SMN2TSHRHTT
SCHEMBL24846292 0.68 GPR84 (0.57) GPR84ALDH1A1
SCHEMBL74104 0.68 DRD2 (1.00) DRD2DRD3KDM4EALOX15ALDH1A1
SCHEMBL21754889 0.68 GPR84 (0.67) GPR84DRD2DRD3KDM4ETSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0460616-B1 Silver halide photographic material FUJI PHOTO FILM CO LTD (JP) 1996-10-16 EP disclosed
US-5238799-A Oxond antirradiation agent FUJI PHOTO FILM CO., LTD. (JP) 1993-08-24 US disclosed
EP-0460616-A1 Silver halide photographic material FUJI PHOTO FILM CO., LTD. (JP) 1991-12-11 EP disclosed
US-4348318-A DYEING AND PRINTING TEXTILES; MONOAZO, TRIAZINE, HYDRAZONE, AND PYRAZOLONE DYES CIBA-GEIGY CORPORATION (US) 1982-09-07 US disclosed