Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | PGK1 | P00558 | 1/20 | 0.36 |
| ▸ | PGK2 | P07205 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9005973 | 0.68 | BCAT2 (0.38) | HDAC6L3MBTL1NPSR1 | |
| SCHEMBL8645093 | 0.67 | PRKAG1 (0.37) | PGK1PGK2NPSR1 | |
| SCHEMBL9700784 | 0.63 | HDAC6 (0.41) | KDM4EHSD17B10PGK1PGK2HDAC6 | |
| SCHEMBL9741731 | 0.63 | — | — | |
| SCHEMBL6666177 | 0.63 | EGFR (0.49) | KDM4EHSD17B10 | |
| SCHEMBL28453316 | 0.61 | SLC22A12 (0.38) | KDM4EHDAC6L3MBTL1NPSR1 | |
| SCHEMBL28447347 | 0.61 | GAA (0.36) | KDM4EHSD17B10HDAC6L3MBTL1NPSR1 | |
| SCHEMBL8644134 | 0.60 | — | — | |
| SCHEMBL9701703 | 0.59 | PLAU (0.34) | — | |
| SCHEMBL9742575 | 0.59 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0736032-A1 | HETEROCYCLIC COMPOUNDS | Astra Aktiebolag (SE) | 1996-10-09 | — | — | EP | disclosed |
| WO-1995017410-A1 | HETEROCYCLIC COMPOUNDS | ASTRA AKTIEBOLAG (SE) | 1995-06-29 | — | — | WO | disclosed |