Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.36 |
| ▸ | PGK1 | P00558 | 1/20 | 0.36 |
| ▸ | PGK2 | P07205 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9700764 | 0.73 | HDAC6 (0.53) | HDAC6L3MBTL1CHRM1KDM4EALDH1A1 | |
| Succinic Acid SCHEMBL30269686 | 0.72 | ALDH1A1 (0.53) | HDAC6L3MBTL1CHRM1KDM4EALDH1A1 | |
| SCHEMBL27693223 | 0.67 | ALDH1A1 (0.42) | KDM4EALDH1A1POLBHPGDHSD17B10 | |
| SCHEMBL9006005 | 0.64 | KDM4E (0.43) | HDAC6CHRM1KDM4EALDH1A1 | |
| SCHEMBL24276933 | 0.64 | HDAC6 (0.46) | HDAC6L3MBTL1CHRM1ALDH1A1PARP1 | |
| SCHEMBL9005979 | 0.63 | KDM4E (0.36) | HDAC6L3MBTL1KDM4EHSD17B10PGK1 | |
| SCHEMBL7650615 | 0.63 | HDAC6 (0.62) | HDAC6L3MBTL1CHRM1KDM4EALDH1A1 | |
| SCHEMBL18989971 | 0.63 | SHMT2 (0.50) | HDAC6L3MBTL1KDM4EALDH1A1 | |
| SCHEMBL31355397 | 0.62 | MAPT (0.52) | L3MBTL1CHRM1KDM4EALDH1A1TP53 | |
| SCHEMBL7450221 | 0.62 | HDAC6 (0.65) | HDAC6L3MBTL1CHRM1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992014740-A1 | QUINOXALINE PHOSPHONO-AMINO ACIDS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1992-09-03 | — | — | WO | claimed |