Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | AURKA | O14965 | 1/20 | 0.48 |
| ▸ | CDK1 | P06493 | 1/20 | 0.48 |
| ▸ | CDK4 | P11802 | 1/20 | 0.48 |
| ▸ | CDK2 | P24941 | 1/20 | 0.48 |
| ▸ | AKT1 | P31749 | 1/20 | 0.48 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.42 |
| ▸ | CLK1 | P49759 | 1/20 | 0.42 |
| ▸ | CLK2 | P49760 | 1/20 | 0.42 |
| ▸ | CLK3 | P49761 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18079552 | 0.84 | AURKA (0.52) | POLBAURKACDK1CDK4CDK2 | |
| SCHEMBL9006329 | 0.82 | NUDT1 (0.41) | AURKACDK1CDK4CDK2AKT1 | |
| SCHEMBL9006179 | 0.82 | PPARA (0.46) | POLBAURKACDK1CDK4CDK2 | |
| SCHEMBL9006235 | 0.82 | HPGD (0.49) | AURKACDK1CDK4CDK2AKT1 | |
| SCHEMBL9006232 | 0.82 | AURKA (0.50) | POLBAURKACDK1CDK4CDK2 | |
| SCHEMBL9006315 | 0.78 | AURKA (0.46) | POLBAURKACDK1CDK4CDK2 | |
| SCHEMBL9006168 | 0.72 | CASP3 (0.42) | POLBAURKAKDM4EHSD17B10KMT2A | |
| SCHEMBL15574603 | 0.71 | NUDT1 (0.60) | AURKACDK1CDK4CDK2AKT1 | |
| SCHEMBL22608957 | 0.71 | NUDT1 (0.50) | POLBAURKACDK1CDK4CDK2 | |
| SCHEMBL8588698 | 0.71 | GSK3A (0.52) | AURKACDK1CDK4CDK2AKT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5506236-A | TREATING HERPES VIRUS INFECTIONS | SCHERING CORPORATION | 1996-04-09 | — | — | US | disclosed |