SCHEMBL9006299

SCHEMBL9006299

Clc1c2ccccc2nc2[nH]ncc12

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.59
MAOB P27338 1/20 0.59
MAPK1 P28482 3/20 0.42
ALDH1A1 P00352 2/20 0.42
TDP1 Q9NUW8 2/20 0.42
PARP1 P09874 1/20 0.42
PRKCI P41743 1/20 0.42
PDE4B Q07343 1/20 0.42
HSD17B10 Q99714 1/20 0.42
NOS1 P29475 3/20 0.40
KDM4E B2RXH2 1/20 0.40
MEN1 O00255 1/20 0.40
GLA P06280 1/20 0.40
GAA P10253 1/20 0.40
MAPT P10636 1/20 0.40
KMT2A Q03164 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.38
CDK2 P24941 2/20 0.38
HSP90AA1 P07900 1/20 0.38
IDO1 P14902 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5470319 0.79 ALDH1A1 (0.59) MAOAMAPK1ALDH1A1TDP1PARP1
SCHEMBL455949 0.76 MAOA (1.00) MAOAMAOBMAPK1ALDH1A1TDP1
SCHEMBL27889436 0.76 MAOA (1.00) MAOAMAOBMAPK1ALDH1A1TDP1
SCHEMBL5478992 0.75 KDM1A (0.66) MAPK1TDP1KDM4EMEN1GLA
Hydrochloric Acid SCHEMBL28400797 0.74 MAOA (0.95) MAOAMAOBMAPK1ALDH1A1TDP1
SCHEMBL17084991 0.71 MAOA (0.44) MAOAMAOBMAPK1ALDH1A1TDP1
SCHEMBL1422547 0.70 MAPT (0.52) MAPK1ALDH1A1TDP1PARP1PRKCI
SCHEMBL29746669 0.70 MAPT (0.52) MAPK1ALDH1A1TDP1PARP1PRKCI
SCHEMBL9006295 0.69 MAOA (0.61) MAOAMAOBALDH1A1TDP1HSD17B10
SCHEMBL15655180 0.69 METAP2 (0.43) MAPK1ALDH1A1HSD17B10NOS1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5506236-A TREATING HERPES VIRUS INFECTIONS SCHERING CORPORATION 1996-04-09 US disclosed