Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 12/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | RAD52 | P43351 | 4/20 | 0.54 |
| ▸ | POLB | P06746 | 3/20 | 0.49 |
| ▸ | GFER | P55789 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | MITF | O75030 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | TOP2A | P11388 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL902770 | 0.80 | KDM1A (1.00) | KDM1AKMT2ARAD52POLBGFER | |
| Hydrochloric Acid SCHEMBL15673452 | 0.79 | KDM1A (0.96) | KDM1AKMT2ARAD52POLBGFER | |
| SCHEMBL17154420 | 0.76 | TGFBR1 (0.57) | KDM1AKMT2ARAD52POLBGFER | |
| SCHEMBL5470319 | 0.75 | ALDH1A1 (0.59) | KMT2ARAD52POLBMAPK1KDM4E | |
| SCHEMBL9006299 | 0.75 | MAOA (0.59) | KMT2AMEN1MAPK1KDM4EMAPT | |
| SCHEMBL92770 | 0.73 | SLC2A1 (0.59) | KMT2ARAD52POLBKDM4EGLA | |
| SCHEMBL11817630 | 0.71 | NPC1 (0.45) | KMT2APOLBMEN1MAPK1MAPT | |
| SCHEMBL23630584 | 0.70 | KDM1A (0.78) | KDM1AKMT2ARAD52POLBGFER | |
| SCHEMBL10061504 | 0.70 | RAD52 (1.00) | KDM1AKMT2ARAD52POLBGFER | |
| SCHEMBL13896217 | 0.70 | MAPK1 (0.59) | KMT2AMEN1MAPK1MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070253957-A1 | Substituted N-Aryl-1H-Pyrazolo[3,4-B]Quinolin-4-Amines and Analogs as Activators of Caspases and Inducers of Apoptosis | CYTOVIA, INC. (US) | 2007-11-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070253957-A1 | Substituted N-Aryl-1H-Pyrazolo[3,4-B]Quinolin-4-Amines and Analogs as Activators of Caspases and Inducers of Apoptosis | CASP3, CASP7, CASP4 | KDM1A 1240/4885KMT2A 2718/4885RAD52 2934/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.