SCHEMBL9006319

SCHEMBL9006319

Cc1ccc(N2C(=O)c3cccc4c(S(=O)(=O)O)ccc(c34)C2=O)c(C)c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.53
LMNA P02545 2/20 0.53
SMN1; SMN2 Q16637 2/20 0.53
MAPK1 P28482 1/20 0.53
BRD1 O95696 9/20 0.45
BRPF1 P55201 9/20 0.45
BRD4 O60885 2/20 0.45
TAF1 P21675 8/20 0.45
MEN1 O00255 3/20 0.44
KMT2A Q03164 3/20 0.44
USP2 O75604 2/20 0.44
KEAP1 Q14145 1/20 0.44
NFE2L2 Q16236 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
KDM4E B2RXH2 1/20 0.44
GAA P10253 1/20 0.43
MAPT P10636 1/20 0.43
CRHBP P24387 1/20 0.43
CASP1 P29466 1/20 0.43
BRCA1 P38398 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13428204 0.86 CLTC (0.47) ALDH1A1LMNASMN1; SMN2MAPK1BRD1
SCHEMBL12203015 0.83 SMN1; SMN2 (0.59) ALDH1A1LMNASMN1; SMN2MAPK1BRD1
SCHEMBL29385571 0.80 KMT2A (0.68) ALDH1A1LMNASMN1; SMN2MAPK1BRD1
SCHEMBL2474686 0.80 KMT2A (0.68) ALDH1A1LMNASMN1; SMN2MAPK1BRD1
SCHEMBL15893573 0.77 ESR1 (0.56) ALDH1A1LMNASMN1; SMN2MAPK1BRD1
SCHEMBL3091743 0.75 MAPT (0.49) ALDH1A1LMNASMN1; SMN2MEN1KMT2A
SCHEMBL28665183 0.74 ESR1 (0.56) ALDH1A1LMNASMN1; SMN2MAPK1MEN1
SCHEMBL20864368 0.74 PKM (0.71) ALDH1A1LMNASMN1; SMN2MAPK1BRD4
SCHEMBL9006326 0.73 CYP1B1 (0.61) ALDH1A1LMNASMN1; SMN2BRD4MEN1
SCHEMBL3828946 0.73 AURKA (0.53) ALDH1A1SMN1; SMN2MEN1KMT2AUSP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0530036-B1 Base board for printed circuit board MITSUBISHI GAS CHEMICAL CO (JP) 1996-10-16 EP disclosed
US-5314740-A Containing a fluorescent dye in the insulating layer to permit accurate inspection by activation MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1994-05-24 US disclosed
EP-0530036-A1 Base board for printed circuit board MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1993-03-03 EP disclosed