SCHEMBL2474686

SCHEMBL2474686

Cc1ccc(N2C(=O)c3cccc4c(N)ccc(c34)C2=O)c(C)c1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 10/20 0.68
USP2 O75604 9/20 0.68
MEN1 O00255 9/20 0.68
KEAP1 Q14145 6/20 0.68
NFE2L2 Q16236 6/20 0.68
L3MBTL1 Q9Y468 1/20 0.68
MAPT P10636 6/20 0.62
RECQL P46063 4/20 0.62
HTT P42858 3/20 0.62
RAB9A P51151 1/20 0.62
RGS12 O14924 3/20 0.59
ATM Q13315 2/20 0.57
SMN1; SMN2 Q16637 4/20 0.57
ALDH1A1 P00352 3/20 0.57
KDM4E B2RXH2 2/20 0.57
LMNA P02545 3/20 0.56
MAPK1 P28482 1/20 0.56
CYP1B1 Q16678 1/20 0.53
THRB P10828 2/20 0.51
NPSR1 Q6W5P4 2/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29385571 1.00 KMT2A (0.68) KMT2AUSP2MEN1KEAP1NFE2L2
SCHEMBL12203015 0.88 SMN1; SMN2 (0.59) KMT2AUSP2MEN1KEAP1NFE2L2
SCHEMBL15893573 0.81 ESR1 (0.56) KMT2AMEN1L3MBTL1MAPTSMN1; SMN2
SCHEMBL9006319 0.80 ALDH1A1 (0.53) KMT2AUSP2MEN1KEAP1NFE2L2
SCHEMBL16449728 0.80 KMT2A (0.82) KMT2AUSP2MEN1KEAP1NFE2L2
SCHEMBL13428204 0.79 CLTC (0.47) KMT2AUSP2MEN1KEAP1NFE2L2
SCHEMBL28665183 0.78 ESR1 (0.56) KMT2AMEN1L3MBTL1MAPTSMN1; SMN2
SCHEMBL14004108 0.77 KMT2A (0.54) KMT2AUSP2MEN1KEAP1NFE2L2
SCHEMBL10662487 0.75 ALDH1A1 (0.67) KMT2AMEN1MAPTRAB9ASMN1; SMN2
SCHEMBL9006270 0.74 KMT2A (1.00) KMT2AUSP2MEN1KEAP1NFE2L2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 96 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5413333-A Colored adhesive for tennis ball seams and a tennis ball seam containing the same GENCORP INC. (US) 1995-05-09 US claimed
US-20260048528-A1 OPTICAL ABSORBING THERMOPLASTIC POLYMER PARTICLES AND METHODS OF PRODUCTION AND USES THEREOF XEROX CORPORATION (US) 2026-02-19 US disclosed
US-20230373130-A1 OPTICAL ABSORBING THERMOPLASTIC POLYMER PARTICLES AND METHODS OF PRODUCTION AND USES THEREOF XEROX CORPORATION (US) 2023-11-23 US disclosed
US-11801617-B2 Optical absorbing thermoplastic polymer particles and methods of production and uses thereof XEROX CORPORATION (US) 2023-10-31 US disclosed
US-20210069935-A1 OPTICAL ABSORBING THERMOPLASTIC POLYMER PARTICLES AND METHODS OF PRODUCTION AND USES THEREOF XEROX CORPORATION (US) 2021-03-11 US disclosed
EP-3789429-A1 OPTICAL ABSORBING THERMOPLASTIC POLYMER PARTICLES AND METHODS OF PRODUCTION AND USES THEREOF Xerox Corporation (US) 2021-03-10 EP disclosed
CN-112457504-A Light absorbing thermoplastic polymer particles and methods of making and using the same 施乐公司 2021-03-09 CN disclosed
CN-108912842-B Liquid crystal printing ink for multiple anti-counterfeiting, preparation method and application 北京化工大学 2020-05-01 CN disclosed
US-20190230766-A1 ORGANIC ELECTROLUMINESCENT DEVICE FUJI XEROX CO., LTD. (JP) 2019-07-25 US disclosed
US-8936858-B2 Organic electroluminescent element and display FUJI XEROX CO., LTD. (JP) 2015-01-20 US disclosed
US-7183009-B2 Organic electroluminescent element FUJI XEROX CO., LTD. (JP) 2007-02-27 US disclosed
EP-0956851-B1 Use of nanotopes in cosmetic products CIBA SC HOLDING AG (CH) 2006-03-08 EP disclosed
US-7008638-B2 Use of nanodispersions in cosmetic end formulations CIBA SPECIALTY CHEMICALS CORPORATION (US) 2006-03-07 US disclosed
US-20050191330-A1 Easily prepared carrier systems for wide range of active agents and oil soluble dyes; homogeneous ethanol and water clear liquid containing phospholipid, endcapped polyoxyethylene coemulsifier and lipophilic triglyceride; wide pH range CIBA SPECIALTY CHEMICALS CORP. 2005-09-01 US disclosed
US-20030068347-A1 Use of microbially encapsulated meterials in cosmetic end formulations CIBA SPECIALTY CHEMICALS CORP. 2003-04-10 US disclosed
EP-1246602-A2 USE OF MICROBIALLY ENCAPSULATED MATERIALS IN COSMETIC END FORMULATIONS Ciba SC Holding AG (CH) 2002-10-09 EP disclosed
US-20020106390-A1 Use of nanodispersions in cosmetic end formulations HUGLIN DIETMAR (DE) 2002-08-08 US disclosed
WO-2001051013-A2 USE OF MICROBIALLY ENCAPSULATED MATERIALS IN COSMETIC END FORMULATIONS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2001-07-19 WO disclosed
EP-0956851-A1 Use of nanotopes in cosmetic products Ciba SC Holding AG (CH) 1999-11-17 EP disclosed
US-5413333-A Colored adhesive for tennis ball seams and a tennis ball seam containing the same GENCORP INC. (US) 1995-05-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260048528-A1 OPTICAL ABSORBING THERMOPLASTIC POLYMER PARTICLES AND METHODS OF PRODUCTION AND USES THEREOF SPOP, RAB5IF, CETP KMT2A 3342/4885USP2 1775/4885MEN1 3250/4885
US-20050191330-A1 Easily prepared carrier systems for wide range of active agents and oil soluble dyes; homogeneous ethanol and water clear liquid containing phospholipid, endcapped polyoxyethylene coemulsifier and lipophilic triglyceride; wide pH range LIPA, CETP, LIPC KMT2A 3899/4885USP2 2490/4885MEN1 3461/4885
US-20030068347-A1 Use of microbially encapsulated meterials in cosmetic end formulations CUTA, MGLL, TMEM205 KMT2A 3363/4885USP2 1796/4885MEN1 37/4885
US-20020106390-A1 Use of nanodispersions in cosmetic end formulations NPC1L1, LIPA, CUTA KMT2A 4592/4885USP2 2066/4885MEN1 3640/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.