Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.50 |
| ▸ | BHMT | Q93088 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.45 |
| ▸ | PPARG | P37231 | 7/20 | 0.45 |
| ▸ | PPARD | Q03181 | 7/20 | 0.45 |
| ▸ | PPARA | Q07869 | 7/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.45 |
| ▸ | TLR2 | O60603 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | FABP4 | P15090 | 2/20 | 0.45 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.45 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | PDE4A | P27815 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9007929 | 0.93 | TSHR (0.50) | TSHRBHMTALDH1A1GPR84PPARG | |
| SCHEMBL8670115 | 0.87 | BHMT (0.51) | TSHRBHMTALDH1A1GPR84PPARG | |
| SCHEMBL17418181 | 0.85 | LMNA (0.58) | TSHRBHMTALDH1A1TDP1KMT2A | |
| SCHEMBL1603479 | 0.85 | GPR84 (0.55) | TSHRALDH1A1GPR84PPARGPPARD | |
| SCHEMBL1603698 | 0.85 | GPR84 (0.55) | TSHRALDH1A1GPR84PPARGPPARD | |
| SCHEMBL9007897 | 0.83 | DGKA (0.46) | TSHRALDH1A1TDP1ALOX15KMT2A | |
| SCHEMBL9264669 | 0.81 | ALDH1A1 (0.64) | TSHRBHMTALDH1A1GPR84PPARG | |
| SCHEMBL16411033 | 0.81 | PLA2G4B (0.54) | TSHRBHMTALDH1A1TDP1KMT2A | |
| SCHEMBL23130978 | 0.81 | ALDH1A1 (0.61) | TSHRALDH1A1GPR84PPARGPPARD | |
| SCHEMBL11503981 | 0.81 | ALDH1A1 (0.61) | TSHRALDH1A1GPR84PPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0441765-B1 | Novel fatty acid analog enzyme substrates | UNIV WASHINGTON (US) | 1994-05-11 | — | — | EP | claimed |
| US-5082967-A | Myristolyation | WASHINGTON UNIVERSITY (US) | 1992-01-21 | — | — | US | claimed |
| EP-0441765-A1 | Novel fatty acid analog enzyme substrates | WASHINGTON UNIVERSITY (US) | 1991-08-14 | — | — | EP | claimed |
| US-5571689-A | Method of N-acylating peptide and proteins with diheteroatom substituted analogs of myristic acid | WASHINGTON UNIVERSITY (US) | 1996-11-05 | — | — | US | disclosed |
| EP-0441765-B1 | Novel fatty acid analog enzyme substrates | UNIV WASHINGTON (US) | 1994-05-11 | — | — | EP | disclosed |
| US-5082967-A | Myristolyation | WASHINGTON UNIVERSITY (US) | 1992-01-21 | — | — | US | disclosed |
| EP-0441765-A1 | Novel fatty acid analog enzyme substrates | WASHINGTON UNIVERSITY (US) | 1991-08-14 | — | — | EP | disclosed |