Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.61 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.51 |
| ▸ | RAF1 | P04049 | 1/20 | 0.51 |
| ▸ | BRAF | P15056 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 11/20 | 0.50 |
| ▸ | CA1 | P00915 | 10/20 | 0.50 |
| ▸ | CA9 | Q16790 | 7/20 | 0.50 |
| ▸ | CA7 | P43166 | 5/20 | 0.50 |
| ▸ | CA13 | Q8N1Q1 | 4/20 | 0.50 |
| ▸ | EGFR | P00533 | 4/20 | 0.50 |
| ▸ | ERBB3 | P21860 | 2/20 | 0.50 |
| ▸ | CA12 | O43570 | 4/20 | 0.49 |
| ▸ | CDK1 | P06493 | 1/20 | 0.48 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.48 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.48 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.48 |
| ▸ | CDK2 | P24941 | 1/20 | 0.48 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.48 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.48 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27962184 | 0.85 | CA1 (0.62) | ROCK1RAF1BRAFCA2CA1 | |
| Sulfadoxine SCHEMBL615997 | 0.82 | ESR1 (0.90) | ESR1CA2CA1CA9CA7 | |
| SCHEMBL10759313 | 0.82 | CA2 (0.54) | ROCK1RAF1BRAFCA2CA1 | |
| SCHEMBL9007901 | 0.81 | ESR1 (0.58) | ESR1POLB | |
| SCHEMBL10695768 | 0.79 | MEN1 (0.58) | ROCK1RAF1BRAFCA2CA1 | |
| Sulfadoxine SCHEMBL41069 | 0.76 | ESR1 (1.00) | ESR1 | |
| Sulfadoxine SCHEMBL29390814 | 0.76 | ESR1 (1.00) | ESR1 | |
| Sulfadoxine SCHEMBL28359083 | 0.75 | ESR1 (0.97) | ESR1 | |
| Sulfadoxine SCHEMBL28436237 | 0.75 | ESR1 (0.97) | ESR1 | |
| Sulfadoxine SCHEMBL28537335 | 0.75 | ESR1 (0.97) | ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0741570-B1 | PREVENTING OR REDUCING PHOTOSENSITIVITY AND/OR PHOTOTOXICITY REACTIONS TO ANTIINFECTIVE MEDICATIONS | SEARLE & CO (US) | 2003-05-07 | — | — | EP | claimed |
| EP-0255100-A2 | Use of trimetrexate and its salts for the preparation of pharmaceutical compositions for treating infections of the mycobacterium-avium-intracellulare complex | WARNER-LAMBERT COMPANY (US) | 1988-02-03 | — | — | EP | claimed |
| US-4284627-A | TETRAHYDROACRIDONE DERIVATIVES | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-08-18 | — | — | US | claimed |
| EP-0001796-B1 | ANTI-MALARIA DRUG | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-06-10 | — | — | EP | claimed |
| CN-217092184-U | Activated carbon decoloring device for precisely processing sulfadoxine | 江苏金申医药科技有限公司 | 2022-08-02 | — | — | CN | disclosed |
| CN-110694319-B | High-purity decolorizing and filter pressing process of sulfadoxine | 江苏金申医药科技有限公司 | 2022-04-01 | — | — | CN | disclosed |
| CN-110642794-B | Efficient preparation method of sulfadoxine cyclic compound intermediate | 江苏金申医药科技有限公司 | 2022-03-08 | — | — | CN | disclosed |
| CN-211051499-U | Stirring mechanism of sulfadoxine reaction tank | 常熟市金申医化制品有限责任公司 | 2020-07-21 | — | — | CN | disclosed |
| CN-211051363-U | Rotary conical stirring equipment | 常熟市金申医化制品有限责任公司 | 2020-07-21 | — | — | CN | disclosed |
| CN-211051037-U | Filter pressing device for preparing sulfadoxine | 常熟市金申医化制品有限责任公司 | 2020-07-21 | — | — | CN | disclosed |
| CN-211051462-U | Sulfadoxine preparation storage tank | 常熟市金申医化制品有限责任公司 | 2020-07-21 | — | — | CN | disclosed |
| CN-211026306-U | A retort for preparing sulfadoxine | 常熟市金申医化制品有限责任公司 | 2020-07-17 | — | — | CN | disclosed |
| US-4374826-A | SULFADOXINE, TRIMETHOPRIM, 2-PYRROLIDONE | PFIZER INC. (US) | 1983-02-22 | — | — | US | disclosed |
| US-4284627-A | TETRAHYDROACRIDONE DERIVATIVES | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-08-18 | — | — | US | disclosed |
| US-4284627-A | TETRAHYDROACRIDONE DERIVATIVES | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-08-18 | — | — | US | disclosed |
| EP-0001796-B1 | ANTI-MALARIA DRUG | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-06-10 | — | — | EP | disclosed |
| US-4260615-A | Antimalarial compositions | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-04-07 | — | — | US | disclosed |
| US-4260615-A | Antimalarial compositions | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-04-07 | — | — | US | disclosed |
| EP-0001796-A1 | Anti-malaria drug | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-05-16 | — | — | EP | disclosed |
| EP-0001796-A1 | Anti-malaria drug | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-05-16 | — | — | EP | disclosed |