Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.44 |
| ▸ | ABAT | P80404 | 1/20 | 0.44 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.38 |
| ▸ | MAPT | P10636 | 6/20 | 0.38 |
| ▸ | ALDH3A1 | P30838 | 2/20 | 0.38 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.38 |
| ▸ | XDH | P47989 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | TTR | P02766 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ERN1 | O75460 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26325 | 0.74 | TSHR (0.48) | ALDH1A1LMNAHPGDSMN1; SMN2 | |
| SCHEMBL4837606 | 0.73 | HSP90AA1 (0.30) | — | |
| SCHEMBL6257261 | 0.72 | SNCA (0.33) | LMNAMEN1KMT2AHTT | |
| Water SCHEMBL28995322 | 0.72 | TSHR (0.46) | ALDH1A1LMNAHPGDSMN1; SMN2 | |
| SCHEMBL6904635 | 0.72 | ALDH1A1 (0.44) | ALDH1A1MAPTLMNAMEN1KMT2A | |
| SCHEMBL590426 | 0.72 | TDP1 (0.44) | VCAM1ALDH1A1MAPTLMNAMEN1 | |
| SCHEMBL387257 | 0.72 | ALDH1A1 (0.44) | VCAM1ALDH1A1MAPTLMNAMEN1 | |
| SCHEMBL2131010 | 0.72 | S100A4 (0.34) | ALDH1A1LMNAMEN1KMT2AERN1 | |
| SCHEMBL441113 | 0.72 | TSHR (0.45) | ALDH1A1MAPTLMNA | |
| SCHEMBL3044183 | 0.72 | ALDH1A1 (0.44) | ALDH1A1MAPTLMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0511917-B1 | Glycosylated prodrugs, process for their preparation and uses thereof | HOECHST SA LAB (FR) | 1996-10-23 | — | — | EP | claimed |
| WO-1992019639-A1 | GLYCOSYLATED PRODRUGS, METHOD OF PREPARATION AND USE | LABORATOIRES HOECHST (FR) | 1992-11-12 | — | — | WO | claimed |
| EP-0511917-A1 | Glycosylated prodrugs, process for their preparation and uses thereof | LABORATOIRES HOECHST S.A. (FR) | 1992-11-04 | — | — | EP | claimed |
| EP-0511917-B1 | Glycosylated prodrugs, process for their preparation and uses thereof | HOECHST SA LAB (FR) | 1996-10-23 | — | — | EP | disclosed |
| WO-1992019639-A1 | GLYCOSYLATED PRODRUGS, METHOD OF PREPARATION AND USE | LABORATOIRES HOECHST (FR) | 1992-11-12 | — | — | WO | disclosed |
| EP-0511917-A1 | Glycosylated prodrugs, process for their preparation and uses thereof | LABORATOIRES HOECHST S.A. (FR) | 1992-11-04 | — | — | EP | disclosed |