Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 3/20 | 0.69 |
| ▸ | NPC1 | O15118 | 3/20 | 0.63 |
| ▸ | RAB9A | P51151 | 3/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.58 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | SMO | Q99835 | 3/20 | 0.55 |
| ▸ | F2R | P25116 | 1/20 | 0.55 |
| ▸ | MAOB | P27338 | 1/20 | 0.54 |
| ▸ | PLAU | P00749 | 2/20 | 0.54 |
| ▸ | PLAT | P00750 | 2/20 | 0.54 |
| ▸ | F2 | P00734 | 1/20 | 0.54 |
| ▸ | F10 | P00742 | 1/20 | 0.54 |
| ▸ | JAK1 | P23458 | 1/20 | 0.53 |
| ▸ | TYK2 | P29597 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5387595 | 0.86 | SMO (0.73) | JAK2NPC1RAB9AMEN1KMT2A | |
| SCHEMBL4155586 | 0.86 | JAK2 (0.73) | JAK2NPC1RAB9AMEN1KMT2A | |
| SCHEMBL10599235 | 0.82 | JAK2 (0.68) | JAK2NPC1RAB9AMEN1KMT2A | |
| SCHEMBL31078080 | 0.79 | RORC (0.82) | JAK2NPC1RAB9AMEN1KMT2A | |
| SCHEMBL15778670 | 0.79 | FADS1 (0.68) | JAK2NPC1RAB9AMEN1KMT2A | |
| SCHEMBL8317875 | 0.78 | NPC1 (0.61) | JAK2NPC1RAB9AMEN1KMT2A | |
| SCHEMBL15779480 | 0.78 | RAB9A (0.61) | JAK2NPC1RAB9AMEN1KMT2A | |
| SCHEMBL5022887 | 0.78 | NPC1 (0.65) | JAK2NPC1RAB9AMEN1KMT2A | |
| SCHEMBL3788790 | 0.77 | ALDH1A1 (0.66) | JAK2NPC1RAB9AMEN1KMT2A | |
| SCHEMBL16743449 | 0.76 | JAK2 (0.56) | JAK2NPC1RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 108 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0331095-B1 | Improving stability at moderate temperatures of motor vehicle components shaped from polyvinyl chloride resin compositions | WITCO CORP (US) | 1996-10-09 | — | — | EP | disclosed |
| EP-0313676-B1 | Bis-(2,2,6,6-tetramethyl-piperidyl) diimides as light stabilizers for synthetic polymers | ADEKA ARGUS CHEMICAL CO LTD (JP) | 1994-01-26 | — | — | EP | disclosed |
| EP-0184203-B1 | VINYL BENZYL 2,2,6,6-TETRAMETHYL PIPERIDINES | ADEKA ARGUS CHEMICAL CO., Ltd. (JP) | 1992-04-15 | — | — | EP | disclosed |
| EP-0209126-B1 | HYDROCARBYL(POLYPHENOL)-POLY(2,2,6,6-TETRAMETHYL PIPERIDYL-1,3,5-TRIAZINES) AS STABILIZERS FOR SYNTHETIC POLYMER COMPOSITIONS | ADEKA ARGUS CHEMICAL CO., Ltd. (JP) | 1992-01-02 | — | — | EP | disclosed |
| EP-0176106-B1 | N,N',N-TRIS((2,2,6,6-TETRAMETHYL-4-PIPERIDYL)TRIAZINYL)-UNDECANE TRIAMINES AS STABILIZERS FOR SYNTHETIC POLYMERS | ADEKA ARGUS CHEMICAL CO., Ltd. (JP) | 1990-11-22 | — | — | EP | disclosed |
| US-4957954-A | TETRAMETHYPIPERIDINYL COMPOUND AND PERCHLORATE | ADEKA ARGUS CHEMICAL CO., LTD. (JP) | 1990-09-18 | — | — | US | disclosed |
| EP-0047894-B2 | HOMOGENEOUS STORAGE-STABLE LIQUID BARIUM-CADMIUM-TRIPHOSPHITE STABILIZER SYSTEMS FOR POLYVINYL CHLORIDE RESINS | Argus Chemical Corporation (US) | 1990-09-05 | — | — | EP | disclosed |
| US-4950704-A | DIKETONE AS HEAT STABILIZER | ARGUS CHEMICAL CORPORATION (US) | 1990-08-21 | — | — | US | disclosed |
| EP-0180992-B1 | STABILIZER COMPOSITIONS FOR SYNTHETIC RESINS IMPARTING IMPROVED LIGHT STABILITY | ADEKA ARGUS CHEMICAL CO., Ltd. (JP) | 1990-07-11 | — | — | EP | disclosed |
| US-4910238-A | Photostable polyvinyl chloride | ADEKA ARGUS CHEMICAL CO. LTD. (JP) | 1990-03-20 | — | — | US | disclosed |
| EP-0046161-A2 | Stabilized Polyvinylhalide resin | PHOENIX CHEMICAL CORPORATION (US) | 1982-02-24 | — | — | EP | disclosed |
| EP-0040286-A2 | Polyvinyl halide resin compositions containing 1,3 Dicarbonyl compounds | PHOENIX CHEMICAL CORPORATION (US) | 1981-11-25 | — | — | EP | disclosed |
| EP-0038876-A1 | 2,6-Di-tertiary butyl phenyl pentaerythritol spiro bis-phosphites enhancing the stability to heat and light of synthetic resins, stabilizer compositions comprising phenolic antioxidants and such phosphites, and synthetic resin compositions containing the same | ADEKA ARGUS CHEMICAL CO., Ltd. (JP) | 1981-11-04 | — | — | EP | disclosed |
| US-4279805-A | Alkylene-bis-thioalkanoic acid amide stabilizers for synthetic resins and synthetic resin compositions containing the same | ARGUS CHEMICAL CORPORATION (US) | 1981-07-21 | — | — | US | disclosed |
| US-4222931-A | Stabilizers for synthetic polymers comprising 2,2,6,6-tetramethyl-4-piperidyl ether alcohol or ether, phosphonic acid ester and phenolic antioxidant | ARGUS CHEMICAL CORPORATION (US) | 1980-09-16 | — | — | US | disclosed |
| US-4219463-A | Stabilizers for synthetic polymers comprising 2,2,6,6-tetramethyl-4-piperidyl carboxylic acid ester, β-thioalkyl propionic acid ester and phenol | ARGUS CHEMICAL CORPORATION (US) | 1980-08-26 | — | — | US | disclosed |
| US-4210577-A | Stabilizers for synthetic polymers comprising 2,2,6,6-tetramethyl-4-piperidyl carboxylic acid ester, phosphonic acid ester and phenol | ARGUS CHEMICAL CORPORATION (US) | 1980-07-01 | — | — | US | disclosed |
| US-4209431-A | OXIDATION AND HEAT RESISTANCE | WITCO CHEMICAL CORPORATION (US) | 1980-06-24 | — | — | US | disclosed |
| US-4080364-A | Stabilization of polyolefins against degradative deterioration as a result of exposure to light and air at elevated temperatures | ARGUS CHEMICAL CORPORATION (US) | 1978-03-21 | — | — | US | disclosed |
| US-3997551-A | OXIDATION RESISTANCE, STABILIZE POLYMERS | ARGUS CHEMICAL CORPORATION (US) | 1976-12-14 | — | — | US | disclosed |