Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM5 | P08912 | 1/20 | 0.41 |
| ▸ | GPR3 | P46089 | 1/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | THRA | P10827 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | EIF4E | P06730 | 1/20 | 0.38 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.38 |
| ▸ | NTRK1 | P04629 | 4/20 | 0.37 |
| ▸ | CTSA | P10619 | 1/20 | 0.37 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.37 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.37 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.37 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.37 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18670146 | 0.78 | NPSR1 (0.49) | EIF4ESCN5ASCN9ACARM1PRMT1 | |
| SCHEMBL468075 | 0.75 | PDPK1 (0.52) | CASP3NTRK1SCN5ASCN9A | |
| SCHEMBL8859981 | 0.75 | FBP1 (0.49) | CARM1PRMT1 | |
| SCHEMBL28251101 | 0.74 | CTSA (0.53) | NTRK1CTSA | |
| SCHEMBL6003163 | 0.72 | ABL1 (0.53) | GPR3ABL1SCN9APIM1CSNK2B | |
| SCHEMBL8684449 | 0.72 | ALDH1A1 (0.41) | THRATHRBCARM1PRMT1 | |
| SCHEMBL29699536 | 0.71 | KMO (0.49) | SCN5ASCN9A | |
| SCHEMBL6482576 | 0.70 | CARM1 (0.47) | THRATHRBCARM1PRMT1 | |
| SCHEMBL27926260 | 0.69 | GPR3 (0.49) | CHRM5GPR3THRATHRBSCN5A | |
| SCHEMBL15194320 | 0.69 | ALDH1A1 (0.46) | THRATHRBCARM1PRMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0742010-A2 | Benzoquinolin-3-ones to inhibit bone loss | ELI LILLY AND COMPANY (US) | 1996-11-13 | — | — | EP | disclosed |