Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 3/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8635292 | 0.90 | CHRM3 (0.34) | CHRM3ALOX5HDAC6 | |
| SCHEMBL9010385 | 0.79 | ALOX5 (0.33) | CHRM3ALOX5HDAC6 | |
| SCHEMBL9010364 | 0.75 | MDM2 (0.35) | — | |
| SCHEMBL8632766 | 0.67 | — | — | |
| SCHEMBL8635963 | 0.67 | AGTR1 (0.45) | — | |
| SCHEMBL9010402 | 0.66 | APLNR (0.38) | CHRM3ALOX5HDAC6 | |
| SCHEMBL8656074 | 0.66 | CHRM3 (0.36) | CHRM3ALOX5HDAC6 | |
| SCHEMBL9010377 | 0.65 | CHRM3 (0.37) | CHRM3ALOX5HDAC6 | |
| SCHEMBL9010380 | 0.65 | CHRM3 (0.36) | CHRM3ALOX5HDAC6 | |
| SCHEMBL8635293 | 0.65 | CHRM3 (0.35) | CHRM3ALOX5HDAC6PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5521206-A | HYPOTENSIVE AGENTS, TREATMENT OF ATHEROSCLEROSIS | BAYER AKTIENGESELLSCHAFT (DE) | 1996-05-28 | — | — | US | disclosed |