Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.48 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.46 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.46 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.45 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.45 |
| ▸ | MGAM | O43451 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | TNKS | O95271 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.42 |
| ▸ | CDK4 | P11802 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11815497 | 0.81 | KDM4E (0.59) | KDM4EHSD17B10ALDH1A1HPGDTSHR | |
| SCHEMBL18035339 | 0.81 | KDM4E (0.59) | KDM4EHSD17B10ALDH1A1HPGDTSHR | |
| SCHEMBL4735747 | 0.78 | IMPDH2 (0.47) | KDM4EHSD17B10ALDH1A1HPGDTSHR | |
| SCHEMBL1622939 | 0.76 | IMPDH2 (0.44) | KDM4EHSD17B10ALDH1A1HPGDTSHR | |
| SCHEMBL17829223 | 0.75 | KDM4E (0.64) | KDM4EHSD17B10ALDH1A1HPGDTSHR | |
| SCHEMBL4142958 | 0.75 | KDM4E (1.00) | KDM4EHSD17B10ALDH1A1HPGDTSHR | |
| SCHEMBL1997257 | 0.73 | TTK (0.56) | KDM4EHSD17B10ALDH1A1HPGDTSHR | |
| Lithium SCHEMBL30669498 | 0.73 | KDM4E (0.96) | KDM4EHSD17B10ALDH1A1HPGDTSHR | |
| SCHEMBL17367227 | 0.72 | KDM4E (0.93) | KDM4EHSD17B10ALDH1A1HPGDTSHR | |
| Urea SCHEMBL15312604 | 0.72 | KDM4E (0.84) | KDM4EHSD17B10ALDH1A1HPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180339972-A1 | LACTONE-BASED PROBES AND METHODS OF USE THEREOF | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2018-11-29 | — | — | US | claimed |
| US-20160376632-A1 | KINASE ACTIVITY DETECTION METHODS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2016-12-29 | — | — | US | claimed |
| US-20160097084-A1 | KINASE ACTIVITY DETECTION METHODS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2016-04-07 | — | — | US | claimed |
| CN-120040356-B | Small molecular fluorescent probe and application thereof in nickel ion detection | 中国烟草总公司安徽省公司 | 2025-12-02 | — | — | CN | disclosed |
| CN-120040356-A | Small molecular fluorescent probe and application thereof in nickel ion detection | 中国烟草总公司安徽省公司 | 2025-05-27 | — | — | CN | disclosed |
| CN-120040356-A | Small molecular fluorescent probe and application thereof in nickel ion detection | 中国烟草总公司安徽省公司 | 2025-05-27 | — | — | CN | disclosed |
| EP-3160517-B1 | WATER-SOLUBLE ACTIVATABLE MOLECULAR PROBES, INTERMEDIATES FOR THE SYNTHESIS THEREOF AND ASSOCIATED DETECTION METHODS | ECOLE NORMALE SUPERIEURE LYON (FR) | 2024-06-12 | — | — | EP | disclosed |
| CN-114478457-B | Activated aggregation-induced emission probe and application thereof in sensitive detection of carbaryl | 中南大学 | 2023-09-22 | — | — | CN | disclosed |
| CN-114478457-A | Activatable aggregation-inducible luminescent probe and application thereof in sensitive detection of carbaryl | 中南大学 | 2022-05-13 | — | — | CN | disclosed |
| CN-106470977-B | Water-soluble activatable molecular probe, synthetic intermediate thereof and related detection method | 里昂高等师范学院 | 2021-07-09 | — | — | CN | disclosed |
| US-11022602-B2 | Antibiotic-based conjugates and methods of use thereof | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2021-06-01 | — | — | US | disclosed |
| US-20160097084-A1 | KINASE ACTIVITY DETECTION METHODS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2016-04-07 | — | — | US | disclosed |
| US-20140234887-A1 | FLUOROGENIC PEPTIDASE SUBSTRATE | CENTRE NATIONAL DE LA RECHERCHE SCIENTFIQUE (FR) | 2014-08-21 | — | — | US | disclosed |
| EP-2760844-A1 | FLUOROGENIC PEPTIDASE SUBSTRATE | Ecole Normale Superieure De Lyon (FR) | 2014-08-06 | — | — | EP | disclosed |
| WO-2013045854-A1 | FLUOROGENIC PEPTIDASE SUBSTRATE | ECOLE NORMALE SUPERIEURE DE LYON (FR) | 2013-04-04 | — | — | WO | disclosed |
| EP-0641351-B1 | ENZYMATIC ANALYSIS USING SUBSTRATES THAT YIELD FLUORESCENT PRECIPITATES | MOLECULAR PROBES INC (US) | 1996-10-23 | — | — | EP | disclosed |
| US-5443986-A | Enzymatic analysis using substrates that yield fluorescent precipitates | MOLECULAR PROBES, INC. (US) | 1995-08-22 | — | — | US | disclosed |
| EP-0641351-A1 | ENZYMATIC ANALYSIS USING SUBSTRATES THAT YIELD FLUORESCENT PRECIPITATES. | MOLECULAR PROBES INC (US) | 1995-03-08 | — | — | EP | disclosed |
| US-5316906-A | Fluorescent dyes for substrates | MOLECULAR PROBES, INC. (US) | 1994-05-31 | — | — | US | disclosed |
| WO-1993004077-A1 | ENZYMATIC ANALYSIS USING SUBSTRATES THAT YIELD FLUORESCENT PRECIPITATES | MOLECULAR PROBES, INC. (US) | 1993-03-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11022602-B2 | Antibiotic-based conjugates and methods of use thereof | MRPL21, RDX, ABCB11 | KDM4E 1609/4885HSD17B10 1472/4885ALDH1A1 1173/4885 |
| US-20180339972-A1 | LACTONE-BASED PROBES AND METHODS OF USE THEREOF | MRPL21, QPCTL, ARGLU1 | KDM4E 2694/4885HSD17B10 953/4885ALDH1A1 2050/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.