Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.45 |
| ▸ | USP36 | Q9P275 | 1/20 | 0.43 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.35 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.33 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.33 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8400032 | 0.84 | GRN (0.46) | KCNH2KMT2A | |
| SCHEMBL8402049 | 0.79 | GPR139 (0.42) | DDR1KMT2A | |
| SCHEMBL8403842 | 0.78 | TAS1R3 (0.46) | SLC6A3KCNH2DDR1TAS1R3TAS1R1 | |
| SCHEMBL8402078 | 0.78 | GRN (0.38) | CNR2KCNH2KMT2A | |
| SCHEMBL9010830 | 0.76 | HDAC1 (0.51) | KMT2A | |
| SCHEMBL9821286 | 0.75 | RAB9A (0.48) | EGFRKMT2A | |
| SCHEMBL9082843 | 0.75 | HPGD (0.48) | PTGS2KDM4ETAS1R3TAS1R1TAS1R2 | |
| SCHEMBL8400028 | 0.74 | HPGD (0.49) | KDM4EKMT2ATAS1R3TAS1R2 | |
| SCHEMBL8403929 | 0.74 | GRN (0.44) | KCNH2KMT2A | |
| SCHEMBL8402033 | 0.73 | LMNA (0.35) | KDM4EDDR1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5547984-A | FUNGICIDES | ROHM AND HAAS COMPANY (US) | 1996-08-20 | — | — | US | disclosed |
| US-5529978-A | FUNGICIDE | ROHM AND HAAS COMPANY (US) | 1996-06-25 | — | — | US | disclosed |
| US-5344978-A | Fungicides | ROHM AND HAAS COMPANY (US) | 1994-09-06 | — | — | US | disclosed |
| US-5196046-A | N-acetonyl-substituted-amides | ROHM AND HAAS COMPANY (US) | 1993-03-23 | — | — | US | disclosed |
| EP-0170498-B1 | N-ACETONYL-SUBSTITUTED-AMIDES, COMPOSITIONS CONTAINING THEM AND THEIR USE IN COMBATING FUNGI | ROHM AND HAAS COMPANY (US) | 1991-09-11 | — | — | EP | disclosed |
| US-4863940-A | N-acetonyl-substituted amides and phytopathogenic fungicidal use thereof | ROHM AND HAAS (US) | 1989-09-05 | — | — | US | disclosed |
| EP-0170498-A2 | N-acetonyl-substituted-amides, compositions containing them and their use in combating fungi | ROHM AND HAAS COMPANY (US) | 1986-02-05 | — | — | EP | disclosed |