Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.55 |
| ▸ | CCR5 | P51681 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | RBP4 | P02753 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27508890 | 0.85 | RAB9A (0.84) | RAB9AALDH1A1CCR5SMN1; SMN2PKM | |
| SCHEMBL7814284 | 0.83 | ALDH1A1 (0.57) | RAB9AALDH1A1CCR5SMN1; SMN2PKM | |
| SCHEMBL9010993 | 0.79 | SMN1; SMN2 (0.60) | RAB9AALDH1A1CCR5SMN1; SMN2NPC1 | |
| SCHEMBL23972333 | 0.79 | AKR1B1 (0.50) | ALDH1A1LMNAKDM4ETDP1TSHR | |
| SCHEMBL31263811 | 0.78 | QDPR (0.48) | ALDH1A1 | |
| SCHEMBL25377908 | 0.78 | QDPR (0.48) | ALDH1A1 | |
| SCHEMBL9011020 | 0.78 | CCR5 (0.55) | ALDH1A1CCR5KDM4E | |
| SCHEMBL9011249 | 0.78 | DRD4 (0.59) | RAB9ALMNANPC1TSHR | |
| SCHEMBL9011030 | 0.78 | USP2 (0.71) | RAB9AALDH1A1SMN1; SMN2LMNANPC1 | |
| SCHEMBL9011061 | 0.77 | CCR5 (0.54) | ALDH1A1CCR5PKMLMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1035178-C | Arylamide derivatives | SS PHARMACEUTICAL CO (JP) | 1997-06-18 | — | — | CN | disclosed |
| US-5532371-A | SIDE EFFECT REDUCTION | SS PHARMACEUTICAL CO., LTD. (JP) | 1996-07-02 | — | — | US | disclosed |
| US-5411972-A | Arylamide derivatives for treating hyperlipemia | SS PHARMACEUTICAL CO., LTD. (JP) | 1995-05-02 | — | — | US | disclosed |
| EP-0607536-A1 | Arylamide derivatives | SS PHARMACEUTICAL CO., LTD. (JP) | 1994-07-27 | — | — | EP | disclosed |