Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 1/20 | 0.60 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.54 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | CCR5 | P51681 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.48 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27303865 | 0.83 | MAPT (0.84) | SMN1; SMN2MAPTNPC1RAB9AEGLN1 | |
| SCHEMBL7813988 | 0.82 | L3MBTL1 (0.58) | SMN1; SMN2MAPTNPC1RAB9ATPSAB1 | |
| SCHEMBL9011266 | 0.79 | ALDH1A1 (0.57) | SMN1; SMN2MAPTHTTALDH1A1GAA | |
| SCHEMBL9011012 | 0.79 | RAB9A (0.62) | SMN1; SMN2NPC1RAB9AHTTCCR5 | |
| SCHEMBL9011241 | 0.77 | NOS2 (0.53) | SMN1; SMN2HTTALDH1A1GAAKDM4E | |
| SCHEMBL23972333 | 0.77 | AKR1B1 (0.50) | MAPTALDH1A1GAATSHRHSD17B10 | |
| SCHEMBL31263811 | 0.76 | QDPR (0.48) | TPSAB1ALDH1A1 | |
| SCHEMBL25377908 | 0.76 | QDPR (0.48) | TPSAB1ALDH1A1 | |
| SCHEMBL9011020 | 0.76 | CCR5 (0.55) | TPSAB1CCR5ALDH1A1KDM4E | |
| SCHEMBL9011249 | 0.76 | DRD4 (0.59) | NPC1RAB9ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1035178-C | Arylamide derivatives | SS PHARMACEUTICAL CO (JP) | 1997-06-18 | — | — | CN | disclosed |
| US-5532371-A | SIDE EFFECT REDUCTION | SS PHARMACEUTICAL CO., LTD. (JP) | 1996-07-02 | — | — | US | disclosed |
| US-5411972-A | Arylamide derivatives for treating hyperlipemia | SS PHARMACEUTICAL CO., LTD. (JP) | 1995-05-02 | — | — | US | disclosed |
| CN-1094039-A | Arylamide derivatives | SS PHARMACEUTICAL CO (JP) | 1994-10-26 | — | — | CN | disclosed |
| EP-0607536-A1 | Arylamide derivatives | SS PHARMACEUTICAL CO., LTD. (JP) | 1994-07-27 | — | — | EP | disclosed |