Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | PNMT | P11086 | 1/20 | 0.36 |
| ▸ | AHR | P35869 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 3/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4465598 | 0.78 | CYP3A4 (0.43) | CYP3A4MAPK1PNMTAHRTDP1 | |
| SCHEMBL1547863 | 0.77 | PNMT (0.62) | CYP3A4PNMTTAAR1IDO1CYP2A6 | |
| SCHEMBL12474340 | 0.77 | TAAR1 (0.36) | CYP3A4MAPK1PNMTAHRTAAR1 | |
| SCHEMBL3727971 | 0.76 | CYP3A4 (0.42) | CYP3A4MAPK1PNMTAHRTDP1 | |
| SCHEMBL10414261 | 0.75 | TAAR1 (0.35) | CYP3A4MAPK1PNMTTAAR1 | |
| SCHEMBL5003742 | 0.75 | PNMT (0.43) | PNMTTAAR1IDO1 | |
| SCHEMBL2090168 | 0.74 | CYP3A4 (0.46) | CYP3A4MAPK1PNMTAHRTDP1 | |
| SCHEMBL2095375 | 0.74 | PNMT (0.65) | CYP3A4MAPK1PNMTAHRTDP1 | |
| SCHEMBL2090165 | 0.74 | CYP3A4 (0.40) | CYP3A4MAPK1PNMTAHRTDP1 | |
| SCHEMBL6305999 | 0.74 | CYP3A4 (0.40) | CYP3A4MAPK1PNMTAHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2621922-A1 | A PROCESS FOR THE SYNTHESIS OF THIO-TRIAZOLO-GROUP CONTAINING COMPOUNDS | BASF SE (DE) | 2013-08-07 | — | — | EP | disclosed |
| US-8426631-B2 | Fungicidal compounds, method for the production thereof, and use thereof to combat damaging fungi, and agents comprising the same | BASF SE (DE) | 2013-04-23 | — | — | US | disclosed |
| WO-2012041858-A1 | A PROCESS FOR THE SYNTHESIS OF THIO-TRIAZOLO-GROUP CONTAINING COMPOUNDS | BASF SE (DE) | 2012-04-05 | — | — | WO | disclosed |
| EP-2311816-A1 | Isoxazoline Compounds and their Use in Pest Control | Sumitomo Chemical Company, Limited (JP) | 2011-04-20 | — | — | EP | disclosed |
| EP-2311817-A1 | Isoxazoline Compounds and their Use in Pest Control | Sumitomo Chemical Company, Limited (JP) | 2011-04-20 | — | — | EP | disclosed |
| EP-2308858-A1 | Isoxazoline Compounds and their Use in Pest Control | Sumitomo Chemical Company, Limited (JP) | 2011-04-13 | — | — | EP | disclosed |
| US-20100304966-A1 | Fungicidal Compounds, Method For the Production Thereof, And Use Thereof To Combat Damaging Fungi, And Agents Comprising The Same | BASF SE (DE) | 2010-12-02 | — | — | US | disclosed |
| US-20100137372-A1 | ISOXAZOLINE COMPOUNDS AND THEIR USE IN PEST CONTROL | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-06-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100137372-A1 | ISOXAZOLINE COMPOUNDS AND THEIR USE IN PEST CONTROL | CYP4X1, PRDX5, PRDX1 | CYP3A4 95/4885MAPK1 3232/4885PNMT 494/4885 |
| US-20100304966-A1 | Fungicidal Compounds, Method For the Production Thereof, And Use Thereof To Combat Damaging Fungi, And Agents Comprising The Same | CYP51A1, ERG28, CAT | CYP3A4 55/4885MAPK1 1845/4885PNMT 591/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.