Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CTSC | P53634 | 4/20 | 0.37 |
| ▸ | CTSK | P43235 | 2/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ANPEP | P15144 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9089272 | 0.78 | TDP1 (0.51) | MEN1KMT2APOLBMAPTSMN1; SMN2 | |
| SCHEMBL8473232 | 0.78 | TDP1 (0.51) | MEN1KMT2APOLBMAPTSMN1; SMN2 | |
| SCHEMBL7172957 | 0.74 | CTSC (0.47) | MEN1KMT2APOLBCTSCCTSK | |
| SCHEMBL10338258 | 0.68 | CTSC (0.45) | CTSCCTSKCTSSCTSLCTSB | |
| SCHEMBL10338259 | 0.68 | CTSC (0.45) | CTSCCTSKCTSSCTSLCTSB | |
| SCHEMBL27617686 | 0.68 | NOTUM (0.48) | MEN1KMT2AMAPT | |
| SCHEMBL8770105 | 0.68 | CTSL (0.45) | POLBCTSCCTSKCTSSSMN1; SMN2 | |
| SCHEMBL31553563 | 0.67 | ALDH1A1 (0.53) | POLB | |
| SCHEMBL9665783 | 0.67 | ALDH1A1 (0.46) | MEN1KMT2APOLBMAPTHSD17B10 | |
| SCHEMBL6006397 | 0.67 | LMNA (0.62) | MEN1KMT2AHDAC8POLBALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5495025-A | Isoindole compounds which are useful as intermediates | HOFFMANN-LA ROCHE INC. (US) | 1996-02-27 | — | — | US | disclosed |