SCHEMBL9012579

SCHEMBL9012579

CN(C)c1ccc(-c2cc(-c3ccc(N(C)C)cc3N(C)C)cc(-c3ccc(N(C)C)cc3)n2)cc1

nearest known ligand 0.41

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
SYK P43405 2/20 0.41
ADK P55263 2/20 0.40
APP P05067 10/20 0.39
MAPT P10636 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
TERT O14746 1/20 0.39
ALDH1A1 P00352 1/20 0.37
ALOX15 P16050 1/20 0.37
TSHR P16473 1/20 0.37
HSD17B10 Q99714 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8660215 0.82 PGR (0.46) SYKADKAPPMAPTTERT
SCHEMBL8621100 0.82 APP (0.42) SYKADKAPPMAPTSMN1; SMN2
SCHEMBL8618775 0.80 MAPT (0.54) SYKADKAPPMAPTSMN1; SMN2
SCHEMBL10977740 0.78 TOP1 (0.45) MAPTSMN1; SMN2ALDH1A1
SCHEMBL8615693 0.74 PSMB5 (0.49) ADKMAPTSMN1; SMN2ALDH1A1
SCHEMBL8621730 0.74 LTB4R (0.55) SYKADKAPPMAPTSMN1; SMN2
SCHEMBL18867181 0.74 ALDH1A1 (0.56) SYKAPPMAPTSMN1; SMN2ALDH1A1
SCHEMBL8616881 0.74 LTB4R (0.55) SYKADKAPPMAPTSMN1; SMN2
SCHEMBL4353469 0.74 LTB4R (0.55) SYKADKAPPMAPTSMN1; SMN2
SCHEMBL8617572 0.74 ALDH1A1 (0.56) SYKAPPMAPTSMN1; SMN2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023085225-A1 METHOD FOR MANUFACTURING RECYCLED RESIN COMPOSITION 住友化学株式会社 2023-05-19 WO disclosed
US-5558700-A QUINAZOLENE OR PYRIDINE ELECTRON DONOR, ELECTRON ACCEPTOR THE PILOT INK CO., LTD. (JP) 1996-09-24 US disclosed
US-4446321-A COLOR FORMERS, CARBON-FREE DUPLICATION STERLING DRUG INC. (US) 1984-05-01 US disclosed
US-4363503-A FOR PRESSURE SENSITIVE CARBONLESS DUPLICATING AND THERMAL MARKING SYSTEMS STERLING DRUG INC. (US) 1982-12-14 US disclosed
EP-0061128-A1 Pyridine compounds, process for their preparation and systems containing them STERLING DRUG INC. (US) 1982-09-29 EP disclosed