Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CD44 | P16070 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30585548 | 0.82 | CYP3A4 (0.35) | PARP1CYP3A4TSHRALDH1A1HPGD | |
| SCHEMBL28511189 | 0.78 | CYP3A4 (0.53) | PARP1CYP3A4TSHRALDH1A1HPGD | |
| SCHEMBL22368621 | 0.75 | PARP1 (0.37) | PARP1CD44MAPT | |
| SCHEMBL15220539 | 0.75 | MEN1 (0.30) | PARP1CYP3A4TDP1ALOX15CASP1 | |
| SCHEMBL19657537 | 0.73 | CREBBP (0.40) | PARP1TSHRALDH1A1MEN1KMT2A | |
| SCHEMBL29130495 | 0.73 | ADRA2A (0.40) | ALDH1A1MEN1GAAKMT2AKDM4E | |
| SCHEMBL31357070 | 0.73 | CREBBP (0.40) | PARP1TSHRALDH1A1MEN1KMT2A | |
| SCHEMBL9230508 | 0.73 | PARP1 (0.36) | PARP1CYP3A4TSHRALDH1A1HPGD | |
| SCHEMBL28506808 | 0.73 | HTR5A (0.35) | CYP3A4ALDH1A1MEN1GAAKMT2A | |
| SCHEMBL1119383 | 0.71 | CD44 (0.46) | PARP1CYP3A4TSHRALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12606533-B2 | 3-phenylpropylamine derivative | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2026-04-21 | — | — | US | disclosed |
| US-20250353824-A1 | 3-PHENYLPROPYLAMINE DERIVATIVE | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2025-11-20 | — | — | US | disclosed |
| US-20160122307-A1 | PERHYDROQUINOXALINE DERIVATIVES | DR. AUGUST WOLFF GMBH & CO. KG ARZNEIMITTEL (DE) | 2016-05-05 | — | — | US | disclosed |
| EP-2997025-A1 | PERHYDROQUINOXALINE DERIVATIVES USEFUL AS ANALGESICS | Dr. August Wolff GmbH & Co. KG Arzneimittel (DE) | 2016-03-23 | — | — | EP | disclosed |
| CN-105209459-A | Perhydroquinoxaline derivatives useful as analgesics | WOLFF AUGUST GMBH & CO KG ARZNEIMITTEL DR | 2015-12-30 | — | — | CN | disclosed |
| WO-2014184355-A1 | PERHYDROQUINOXALINE DERIVATIVES USEFUL AS ANALGESICS | DR. AUGUST WOLFF GMBH & CO. KG ARZNEIMITTEL (DE) | 2014-11-20 | — | — | WO | disclosed |
| CN-101821254-A | Adrenergic compounds | ALLERGAN INC | 2010-09-01 | — | — | CN | disclosed |
| US-5589476-A | TREATMENT OF NAUSEA, VOMITING AND GASTROINTESTINAL DISORDERS | SYNTHELABO (FR) | 1996-12-31 | — | — | US | disclosed |
| CN-1109471-A | Derivative of imidazol-4yl-piperidine, preparation of same and application of same in treatment | SYNTHELABO (FR) | 1995-10-04 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250353824-A1 | 3-PHENYLPROPYLAMINE DERIVATIVE | SF1, SF3A1, SFXN1 | PARP1 948/4885CYP3A4 957/4885TSHR 1698/4885 |
| US-20160122307-A1 | PERHYDROQUINOXALINE DERIVATIVES | PTGS1, HPGD, HMOX1 | PARP1 605/4885CYP3A4 346/4885TSHR 4732/4885 |
| US-12606533-B2 | 3-phenylpropylamine derivative | SF3A1, SF1, HTR1D | PARP1 1132/4885CYP3A4 609/4885TSHR 1117/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.