SCHEMBL9013176

SCHEMBL9013176

C=Cc1cc(=O)c(OCc2ccccc2)c[nH]1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK14 Q16539 2/20 0.44
L3MBTL1 Q9Y468 3/20 0.42
PPARG P37231 2/20 0.42
NSD2 O96028 1/20 0.42
ABL1 P00519 1/20 0.42
RIN1 Q13671 1/20 0.42
NCOR2 Q9Y618 1/20 0.42
SIRT2 Q8IXJ6 1/20 0.41
POLB P06746 2/20 0.40
GSTP1 P09211 1/20 0.40
GSK3B P49841 1/20 0.40
CCNB2 O95067 1/20 0.39
CDK1 P06493 1/20 0.39
CDK4 P11802 1/20 0.39
CCNB1 P14635 1/20 0.39
CCND1 P24385 1/20 0.39
CCNB3 Q8WWL7 1/20 0.39
MAPT P10636 2/20 0.38
TDP1 Q9NUW8 2/20 0.38
MAPK1 P28482 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9785325 0.87 L3MBTL1 (0.43) MAPK14L3MBTL1PPARGNSD2ABL1
SCHEMBL9650615 0.81 PTGER4 (0.53) ALDH1A1KDM4ELMNA
SCHEMBL9650626 0.81 PTGER4 (0.53) ALDH1A1KDM4ELMNA
SCHEMBL2116326 0.79 L3MBTL1 (0.54) MAPK14L3MBTL1PPARGNSD2ABL1
SCHEMBL9012908 0.75 L3MBTL1 (0.43) MAPK14L3MBTL1PPARGNSD2ABL1
SCHEMBL9653085 0.75 LOXL2 (0.48) MAPK14L3MBTL1PPARGNSD2ABL1
SCHEMBL71120 0.75 GSTP1 (0.44) L3MBTL1PPARGNSD2ABL1RIN1
SCHEMBL2492367 0.75 SRD5A2 (0.52) L3MBTL1PPARGNSD2ABL1RIN1
Hydrochloric Acid SCHEMBL10894906 0.74 L3MBTL1 (0.42) MAPK14L3MBTL1PPARGNSD2ABL1
SCHEMBL2116953 0.74 L3MBTL1 (0.42) MAPK14L3MBTL1PPARGNSD2ABL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0345671-B1 Cephem compounds and processes for preparation thereof FUJISAWA PHARMACEUTICAL CO (JP) 1996-08-21 EP disclosed
US-5532354-A ANTIBIOTICS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1996-07-02 US disclosed
US-5401734-A MICROBIOCIDES FUJISAWA PHAMACEUTICAL CO., LTD. (JP) 1995-03-28 US disclosed
US-5244890-A Treatment of infectious diseases FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1993-09-14 US disclosed
EP-0345671-A2 Cephem compounds and processes for preparation thereof FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1989-12-13 EP disclosed