SCHEMBL9012908

SCHEMBL9012908

O=c1cc(CCl)[nH]cc1OCc1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.43
NSD2 O96028 1/20 0.43
ABL1 P00519 1/20 0.43
PPARG P37231 1/20 0.43
RIN1 Q13671 1/20 0.43
NCOR2 Q9Y618 1/20 0.43
POLB P06746 1/20 0.41
GSTP1 P09211 1/20 0.41
LMNA P02545 1/20 0.41
MAPK14 Q16539 3/20 0.40
MAPT P10636 1/20 0.39
MAPK1 P28482 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
MAOB P27338 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL10894906 0.99 L3MBTL1 (0.42) L3MBTL1NSD2ABL1PPARGRIN1
SCHEMBL9653085 0.85 LOXL2 (0.48) L3MBTL1NSD2ABL1PPARGRIN1
SCHEMBL71120 0.85 GSTP1 (0.44) L3MBTL1NSD2ABL1PPARGRIN1
SCHEMBL16229042 0.83 NPC1 (0.43) POLBTDP1MAOB
SCHEMBL10672044 0.82 GSTP1 (0.41) L3MBTL1NSD2ABL1PPARGRIN1
SCHEMBL13462058 0.82 LMNA (0.50) L3MBTL1NSD2ABL1PPARGRIN1
SCHEMBL9012870 0.82 HTR2A (0.43) L3MBTL1NSD2ABL1PPARGRIN1
SCHEMBL2116326 0.80 L3MBTL1 (0.54) L3MBTL1NSD2ABL1PPARGRIN1
SCHEMBL71232 0.80 ELANE (0.39) L3MBTL1NSD2ABL1PPARGRIN1
SCHEMBL4145610 0.80 ALDH1A1 (0.53) L3MBTL1MAPTTDP1MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0345671-B1 Cephem compounds and processes for preparation thereof FUJISAWA PHARMACEUTICAL CO (JP) 1996-08-21 EP disclosed
US-5532354-A ANTIBIOTICS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1996-07-02 US disclosed
US-5401734-A MICROBIOCIDES FUJISAWA PHAMACEUTICAL CO., LTD. (JP) 1995-03-28 US disclosed
CN-1025737-C Cephem compounds and processes for preparation thereof FUJISAWA PHARMACEUTICAL CO (JP) 1994-08-24 CN disclosed
US-5244890-A Treatment of infectious diseases FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1993-09-14 US disclosed
CN-1038814-A Cephem compound and preparation method thereof FUJISAWA PHARMACEUTICAL CO (JP) 1990-01-17 CN disclosed
EP-0345671-A2 Cephem compounds and processes for preparation thereof FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1989-12-13 EP disclosed
US-4743685-A 2-oxo-1-[[(substituted sulfonyl)amino]carbonyl]azetidines E. R. SQUIBB & SONS, INC. (US) 1988-05-10 US disclosed