SCHEMBL9653085

SCHEMBL9653085

NCc1cc(=O)c(OCc2ccccc2)c[nH]1

nearest known ligand 0.48

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
LOXL2 Q9Y4K0 1/20 0.48
NSD2 O96028 1/20 0.43
ABL1 P00519 1/20 0.43
PPARG P37231 1/20 0.43
RIN1 Q13671 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
NCOR2 Q9Y618 1/20 0.43
LTA4H P09960 2/20 0.42
PLA2G2A P14555 1/20 0.42
TRPM8 Q7Z2W7 1/20 0.42
MAPK14 Q16539 1/20 0.42
MAOB P27338 2/20 0.42
POLB P06746 1/20 0.41
GSTP1 P09211 1/20 0.41
LMNA P02545 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9012908 0.85 L3MBTL1 (0.43) NSD2ABL1PPARGRIN1L3MBTL1
SCHEMBL71120 0.85 GSTP1 (0.44) NSD2ABL1PPARGRIN1L3MBTL1
Hydrochloric Acid SCHEMBL10894906 0.84 L3MBTL1 (0.42) LOXL2NSD2ABL1PPARGRIN1
SCHEMBL13462058 0.82 LMNA (0.50) NSD2ABL1PPARGRIN1L3MBTL1
SCHEMBL10672044 0.82 GSTP1 (0.41) NSD2ABL1PPARGRIN1L3MBTL1
SCHEMBL9012870 0.82 HTR2A (0.43) NSD2ABL1PPARGRIN1L3MBTL1
SCHEMBL2116326 0.80 L3MBTL1 (0.54) NSD2ABL1PPARGRIN1L3MBTL1
SCHEMBL71232 0.80 ELANE (0.39) NSD2ABL1PPARGRIN1L3MBTL1
SCHEMBL9012871 0.80 HTR2A (0.52) TRPM8POLBLMNA
SCHEMBL4145610 0.80 ALDH1A1 (0.53) L3MBTL1MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104529885-A Hyroxy-pyridone derivative with multiple biological activities and usage thereof UNIV ZHEJIANG GONGSHANG 2015-04-22 CN claimed
CN-104529885-B Has multiple bioactive pyridone ketone derivatives and application thereof 浙江工商大学 2016-06-22 CN disclosed
CN-104529885-A Hyroxy-pyridone derivative with multiple biological activities and usage thereof UNIV ZHEJIANG GONGSHANG 2015-04-22 CN disclosed
EP-0243924-B1 2-OXO-1-(SUBSTITUTED PHOSPHOROUS)AZETIDINES E.R. Squibb & Sons, Inc. (US) 1992-12-23 EP disclosed
US-4743685-A 2-oxo-1-[[(substituted sulfonyl)amino]carbonyl]azetidines E. R. SQUIBB & SONS, INC. (US) 1988-05-10 US disclosed
US-4723002-A 1-(substituted phosphorous)-azetidinone antibacterials E. R. SQUIBB & SONS, INC. 1988-02-02 US disclosed
EP-0243924-A2 2-Oxo-1-(substituted phosphorous)azetidines E.R. Squibb & Sons, Inc. (US) 1987-11-04 EP disclosed