Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.37 |
| ▸ | FDPS | P14324 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | GLI1 | P08151 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | ATP4A | P20648 | 1/20 | 0.36 |
| ▸ | ATP4B | P51164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4765782 | 0.80 | HPGD (0.51) | LMNAMAPTHPGDMAPK1L3MBTL1 | |
| SCHEMBL9870409 | 0.79 | GPR84 (0.47) | LMNAPOLBMAPTHPGDTSHR | |
| SCHEMBL4767404 | 0.78 | HPGD (0.40) | MAPTHPGDHDAC1GRIN2BTAAR1 | |
| SCHEMBL9012401 | 0.77 | HDAC1 (0.52) | POLBMAPTHPGDHDAC1GRIN2B | |
| SCHEMBL9012067 | 0.77 | HDAC1 (0.46) | HPGDTSHRHDAC1GRIN2BTAAR1 | |
| SCHEMBL6483534 | 0.74 | RAB9A (0.64) | LMNAMAPTHPGDTSHRMAPK1 | |
| SCHEMBL9011939 | 0.74 | HDAC1 (0.45) | HPGDTSHRHDAC1GRIN2BTAAR1 | |
| SCHEMBL9012190 | 0.73 | HDAC1 (0.44) | HPGDTSHRHDAC1GRIN2BGRIN2A | |
| SCHEMBL9695295 | 0.73 | TP53 (0.67) | LMNAPOLBHPGDNPSR1GRIN2B | |
| SCHEMBL229404 | 0.73 | HDAC1 (0.53) | LMNAHDAC1GRIN2BTAAR1GRIN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5523317-A | ADMINISTERING IMIDAZOLE DERIVATIVE | NIPPON CHEMIPHAR CO., LTD. (JP) | 1996-06-04 | — | — | US | disclosed |
| EP-0354788-B1 | Novel imidazole derivatives | NIPPON CHEMIPHAR CO (JP) | 1995-09-13 | — | — | EP | disclosed |
| EP-0633026-A1 | Use of imidazole derivative for antihypertensive agent | NIPPON CHEMIPHAR CO., LTD. (JP) | 1995-01-11 | — | — | EP | disclosed |
| CN-1020902-C | IMIDAZOLE DERIVATIVE AND PROCESSES FOR PREPARING SAME | TANAHBE SEIYAKU CO LTD (JP) | 1993-05-26 | — | — | CN | disclosed |
| US-5180836-A | Antiulcer agents | NIPPON CHEMIPHAR CO., LTD. (JP) | 1993-01-19 | — | — | US | disclosed |
| US-5082943-A | Antiulcer | NIPPON CHEMIPHAR CO., LTD. (JP) | 1992-01-21 | — | — | US | disclosed |
| EP-0354788-A1 | Novel imidazole derivatives | NIPPON CHEMIPHAR CO., LTD. (JP) | 1990-02-14 | — | — | EP | disclosed |
| CN-87108111-A | Novel imidazole derivative and preparation method thereof | — | 1988-09-28 | — | — | CN | disclosed |