Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9838119 | 0.79 | POLB (0.67) | MAPTNPSR1POLBLMNATSHR | |
| SCHEMBL9013455 | 0.79 | LMNA (0.41) | MAPTNPSR1POLBLMNATSHR | |
| SCHEMBL9872406 | 0.76 | KMT2A (0.72) | LMNATSHRALDH1A1HPGDMAPK1 | |
| SCHEMBL11338091 | 0.75 | MAPT (0.57) | GPR84GLAMAPTNPSR1POLB | |
| SCHEMBL8656211 | 0.73 | HPGD (0.39) | MAPTNPSR1POLBLMNATSHR | |
| SCHEMBL9695295 | 0.73 | TP53 (0.67) | NPSR1POLBLMNAHSD17B10ALDH1A1 | |
| SCHEMBL8658166 | 0.71 | AR (0.39) | MAPTNPSR1POLBLMNATDP1 | |
| SCHEMBL6483534 | 0.71 | RAB9A (0.64) | MAPTNPSR1LMNATSHRHSD17B10 | |
| SCHEMBL9870574 | 0.71 | GLA (0.61) | GLAMAPTNPSR1LMNATSHR | |
| SCHEMBL26034712 | 0.71 | GPR84 (0.66) | GPR84GLAMAPTNPSR1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0391254-A2 | Novel thiouracil derivatives pharmaceutical compositions containing them and process for preparing same | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1990-10-10 | — | — | EP | claimed |
| US-5037830-A | Antisecretory-antiulcer agents | RICHTER GEDEON VEGYESZETI GYAR RT (HU) | 1991-08-06 | — | — | US | disclosed |
| EP-0391254-A2 | Novel thiouracil derivatives pharmaceutical compositions containing them and process for preparing same | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1990-10-10 | — | — | EP | disclosed |