Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | TLR4 | O00206 | 1/20 | 0.36 |
| ▸ | HCAR1 | Q9BXC0 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.32 |
| ▸ | GABRP | O00591 | 1/20 | 0.31 |
| ▸ | GABRD | O14764 | 1/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.31 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30792330 | 0.77 | TLR4 (0.39) | ALDH1A1TLR4HCAR1KMT2AKDM4E | |
| SCHEMBL4127785 | 0.75 | TLR4 (0.38) | ALDH1A1TLR4HCAR1L3MBTL1KMT2A | |
| SCHEMBL9330752 | 0.74 | LMNA (0.51) | ALDH1A1MAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL31615356 | 0.74 | HCAR1 (0.41) | ALDH1A1TLR4HCAR1SMN1; SMN2MEN1 | |
| SCHEMBL28549832 | 0.73 | MAPT (0.46) | ALDH1A1MAPTTP53ALOX12SMN1; SMN2 | |
| SCHEMBL10372172 | 0.72 | MAPK1 (0.39) | ALDH1A1MAPTTLR4HCAR1SMN1; SMN2 | |
| SCHEMBL3438253 | 0.72 | DDB1 (0.50) | ALDH1A1MAPTTLR4HCAR1TP53 | |
| SCHEMBL28557786 | 0.72 | ALDH1A1 (0.47) | ALDH1A1MAPTTP53ALOX12SMN1; SMN2 | |
| SCHEMBL23109084 | 0.70 | ESR2 (0.39) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| Ethylene SCHEMBL27706119 | 0.69 | DDB1 (0.47) | ALDH1A1MAPTTLR4HCAR1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5550118-A | THROMBOXANE SYNTHETASE INHIBITORS, ANTICOAGULANTS | ELI LILLY AND COMPANY (US) | 1996-08-27 | — | — | US | disclosed |
| EP-0665227-A1 | Polyhydronorharman synthase inhibitors | ELI LILLY AND COMPANY (US) | 1995-08-02 | — | — | EP | disclosed |